Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound   Target Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound

---

Query: KEGG:D00307 (Doxycycline)
1,090 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein Sep 75 matrix metalloproteinase 63 MMP-9 42 MMP-2 39 Mol 36 collagen 35 MIC 27 transactivator 18 cytokine 14 collagenase 14 metalloproteinase 12 Pseudomonas 12 p53 11 lipopolysaccharide 11 insulin 11 TNF 10 She 9 IL-6 9 elastin 9 vascular endothelial growth factor 8 tumor necrosis factor 8 EPA 8 MMP 8 MMP-8 8 TNF-alpha 7 p38 7 ROS 7 SDS 6 MMP-13 6 inducible nitric oxide synthase 6 MAPK 6 ATP 6 gut 6 LPS 6 E-cadherin 6 catenin 5 MRSA 5 tyrosine hydroxylase 5 matrix metalloproteinase 2 5 ERK1 5 more...

Disease cancer 67 tumor 51 malaria 38 infectious diseases 35 Lyme disease 34 Chlamydia 31 Mycoplasma 31 breast cancer 22 rash 21 Q fever 21 periodontitis 19 Infection 19 syphilis 18 pneumonia 17 ehrlichiosis 16 HIV 16 brucellosis 16 leptospirosis 15 thrombocytopenia 13 plaque 13 hypertension 13 worms 12 filariasis 12 tumor growth 12 diabetes 11 carcinoma 11 urethritis 11 pelvic inflammatory disease 11 acne 11 zoonosis 11 typhus 10 osteoarthritis 10 scrub typhus 10 arthritis 10 rosacea 10 cholera 10 onchocerciasis 10 Mycobacterium 10 hepatitis 9 anthrax 9 more...

Symptom headache 24 pain 19 diarrhea 15 cough 13 erythema 13 Ill 10 anorexia 8 myalgia 8 weakness 8 dyspnea 7 abdominal pain 6 arthralgia 6 fatigue 6 fever of unknown origin 5 nausea 5 seizures 4 chills 4 anesthesia 4 splenomegaly 4 lethargy 4 vomiting 4 respiratory distress 4 sore throat 3 chest pain 3 cachexia 2 hepatomegaly 2 flushing 2 paresthesia 2 angina 2 discomfort 2 hemoptysis 2 back pain 2 epigastric pain 2 hoarseness 2 photophobia 2 urethral discharge 2 discomfort 2 stridor 1 skin irritation 1 tachypnea 1 more...

Drug Doxycycline 1090 Dermatol 23 ampicillin 22 DOXY 16 Azithromycin 15 Amoxicillin 11 Vibramycin 8 OTC 7 IPM 7 ROS 7 CSF 6 Ofloxacin 6 Atovaquone 5 Monit 4 CTC 4 Meropenem 3 Cardiovasc 3 Malarone 3 CTX 3 Moxifloxacin 3 Demeclocycline 3 Augmentin 3 Isotretinoin 3 Primaquine 3 Retinoic acid 3 AMC 3 G418 3 Meropenem 3 Glutathione 2 Atovaquone 2 Florfenicol 2 CMZ 2 Nitric Oxide 2 CPZ 2 Augmentin 2 Enrofloxacin 2 Trib 2 Kenyan 2 CPFX 2 Oxacillin 2 more...

Enzyme collagenase 16 mitogen-activated protein kinase 14 ERK 11 focal adhesion kinase 11 MMP 8 luciferase 7 beta-lactamase 7 aspartate aminotransferase 6 caspase-3 5 alanine aminotransferase 5 tyrosine hydroxylase 5 MMP-3 5 MEK 4 matrix metalloproteinase 9 4 elastase 4 neutrophil collagenase 4 calcineurin 4 firefly luciferase 3 alkaline phosphatase 3 beta-galactosidase 3 catalase 3 matrix metalloproteinase 2 3 plasmin 3 peroxidase 3 protein kinase 3 neutrophil elastase 3 proteasome 3 cathepsin G 2 NO synthase 2 MDR 2 RNA polymerase 2 GTP cyclohydrolase I 2 cytochrome oxidase 2 cdc2 2 P-glycoprotein 2 RNase III 2 ATPase 2 topoisomerase 2 caspase-9 2 topoisomerase 2 more...

Compound Doxycycline 1073 Dec 77 Clin 73 water 54 DNA 53 Tetracycline 29 MIC 27 oxygen 24 Ciprofloxacin 22 calcium 20 Minocycline 19 Erythromycin 16 Azithromycin 15 Amoxicillin 14 glucose 13 phosphate 12 sodium 12 acetate 12 MDA 11 Penicillin 11 TNF 10 Chloroquine 10 Chloroquine 10 Clindamycin 10 CAM 9 Rifampicin 9 iron 9 NIDA 9 zinc 9 Gentamicin 9 hydrogen 9 nitric oxide 8 Penicillin 8 arginine 7 sulfate 7 Imipenem 7 Oxytetracycline 7 cysteine 7 MTT 6 Ofloxacin 6 more...

---