Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: KEGG:D00253 (Sinemet)
217 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
CD11c 14
prolactin 8
Sep 8
growth hormone 6
dopa decarboxylase 6
OMD 6
tyrosine hydroxylase 5
CR3 5
catechol-O-methyltransferase 4
Pol 3
COMT 3
CSF 3
TRH 2
She 2
Gen 2
STD 2
gut 2
ADL 1
Prolactin 1
ubiquitin 1
5-HT2A 1
MRS 1
insulin 1
MAO-A 1
thyrotropin-releasing hormone 1
glutamate binding 1
MRSA 1
PRL 1
glial cell line-derived neurotrophic factor 1
NMR 1
adenylate cyclase 1
CTP 1
Parkin 1
N-acetylaspartate 1
CPK 1
thyroid hormone 1
parkin 1
dopamine beta-hydroxylase 1
SCH 1
catechol O-methyltransferase 1
more...
Disease
Parkinson's disease 127
parkinsonism 25
dyskinesia 22
akinesia 8
hallucinations 8
abnormal involuntary movements 6
progressive supranuclear palsy 4
confusion 3
psychosis 3
movement disorder 2
renal failure 2
STD 2
Huntington's disease 2
tumor 2
cold 2
hydrocephalus 2
dementia 2
diabetes 1
incontinence 1
pulmonary edema 1
bronchogenic carcinoma 1
abortion 1
drug withdrawal 1
torsion dystonia 1
diabetic retinopathy 1
memory impairment 1
Locked-in syndrome 1
hypertension 1
psoriasis 1
peripheral neuropathy 1
encephalopathy 1
retinopathy 1
infiltrating ductal carcinoma 1
pulmonary embolism 1
respiratory infection 1
gastric retention 1
MRSA 1
schizophrenia 1
phenylketonuria 1
myocardial infarction 1
more...
Symptom
tremor 21
bradykinesia 15
dystonia 10
nausea 6
chorea 4
vomiting 3
muscle rigidity 2
pain 2
blurred vision 2
diarrhea 2
paresis 2
ataxic gait 2
dysarthria 2
ataxia 1
nausea and vomiting 1
livedo 1
headache 1
anesthesia 1
seizures 1
myoclonus 1
angina 1
neurological disability 1
weakness 1
hypotonia 1
exhaustion 1
Drug
Sinemet 217
Sinemet 215
Sinemet 215
Madopar 20
Eldepryl 7
Eldepryl 6
Carbidopa 4
CSF 3
vitamin E 3
Cogentin 2
Lisuride 2
Cogentin 2
Bendrofluazide 1
Vitamin E 1
Tocopherol 1
Parkin 1
Benserazide 1
Methotrexat 1
Fraction 1
Parkin 1
Leucovorin 1
Horizon 1
Anafranil 1
ascorbate 1
TiO2 1
Zyban 1
Ritanserin 1
Lergotrile 1
Ludiomil 1
Parlodel 1
Artane 1
Artane 1
Parlodel 1
Permax 1
Ludiomil 1
Reserpine 1
Akineton 1
Diamminedichloroplatinum 1
Permax 1
Doxepine 1
more...
Enzyme
monoamine oxidase 6
tyrosine hydroxylase 5
focal adhesion kinase 2
DOPA decarboxylase 2
aromatic L-amino acid decarboxylase 2
diamine oxidase 1
PST 1
dopamine beta-hydroxylase 1
DMT 1
dihydropteridine reductase 1
catechol O-methyltransferase 1
adenylate cyclase 1
Compound
Clin 39
L-DOPA 37
Dec 14
Dopamine 8
MPTP 6
water 4
noradrenaline 4
Bromocriptine 4
TRH 3
iron 3
hydroxyindoleacetic acid 3
Dopa 3
calcium 2
5-hydroxytryptophan 2
Selegiline 2
TSH 2
His 2
Amantadine 2
Carbidopa-levodopa 2
5-HT 2
A 42 2
Tolcapone 2
sodium 2
Amantadine 1
DMT 1
DSM 1
aluminum 1
Noveril 1
Diazepam 1
formaldehyde 1
APS 1
Neurotol 1
ammonia 1
EDTA 1
CIT 1
DMT 1
methanol 1
Doxepin hydrochloride 1
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine 1
Ivermectin 1
more...