Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: KEGG:D00253 (
Sinemet
)
217
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
CD11c
14
prolactin
8
Sep
8
dopa decarboxylase
6
OMD
6
growth hormone
6
tyrosine hydroxylase
5
CR3
5
catechol-O-methyltransferase
4
COMT
3
Pol
3
CSF
3
TRH
2
STD
2
Gen
2
She
2
gut
2
PRL
1
Prolactin
1
CPK
1
more...
Disease
Parkinson's disease
127
parkinsonism
25
dyskinesia
22
akinesia
8
hallucinations
8
abnormal involuntary movements
6
progressive supranuclear palsy
4
confusion
3
psychosis
3
Huntington's disease
2
cold
2
tumor
2
STD
2
movement disorder
2
renal failure
2
dementia
2
hydrocephalus
2
psoriasis
1
infiltrating ductal carcinoma
1
incontinence
1
more...
Symptom
tremor
21
bradykinesia
15
dystonia
10
nausea
6
chorea
4
vomiting
3
muscle rigidity
2
blurred vision
2
paresis
2
pain
2
diarrhea
2
ataxic gait
2
dysarthria
2
ataxia
1
nausea and vomiting
1
livedo
1
headache
1
anesthesia
1
seizures
1
myoclonus
1
more...
Drug
Sinemet
217
Sinemet
215
Sinemet
215
Madopar
20
Eldepryl
7
Eldepryl
6
Carbidopa
4
vitamin E
3
CSF
3
Cogentin
2
Cogentin
2
Lisuride
2
Ludiomil
1
Permax
1
Artane
1
Parkin
1
Benserazide
1
Fraction
1
Parkin
1
Leucovorin
1
more...
Enzyme
monoamine oxidase
6
tyrosine hydroxylase
5
focal adhesion kinase
2
DOPA decarboxylase
2
aromatic L-amino acid decarboxylase
2
diamine oxidase
1
PST
1
dopamine beta-hydroxylase
1
DMT
1
dihydropteridine reductase
1
catechol O-methyltransferase
1
adenylate cyclase
1
Compound
Clin
39
L-DOPA
37
Dec
14
Dopamine
8
MPTP
6
water
4
Bromocriptine
4
noradrenaline
4
hydroxyindoleacetic acid
3
Dopa
3
TRH
3
iron
3
Carbidopa-levodopa
2
5-hydroxytryptophan
2
calcium
2
A 42
2
Amantadine
2
Tolcapone
2
sodium
2
5-HT
2
more...