Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: HUMANGGP:041245 (CYP1A2)
 3,969 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
CYP1A2 3969
cytochrome P450 1771
CYP3A4 1439
CYP1A1 1188
CYP2D6 1107
CYP2C9 950
CYP2E1 924
CYP2C19 885
P450 827
CYP2B6 526
microsomal 478
CYP3A 464
CYP 443
CYP2A6 413
CYP2C8 353
cytochrome 317
CYP1B1 317
Sep 293
NADPH 239
xenobiotic 197
more...
Disease
cancer 336
carcinogenesis 171
hepatocellular carcinoma 110
tumor 98
breast cancer 65
schizophrenia 54
GSH 50
depression 47
lung cancer 33
liver disease 32
MCF 26
diabetes 26
cirrhosis 24
colorectal cancer 23
prostate cancer 23
HIV 22
obesity 22
carcinoma 21
NAME 21
hypertension 21
more...
Symptom
pain 13
hyperoxia 11
nausea 9
vomiting 7
anesthesia 7
headache 7
insomnia 5
seizures 5
angina 4
diarrhea 4
respiratory distress 4
dizziness 4
sleepiness 4
hepatomegaly 4
tremor 3
menopausal symptoms 3
cough 3
agitation 2
starvation 2
analgesia 2
more...
Drug
caffeine 380
Ketoconazole 27
Leaf 23
Monit 17
Mutagen 17
PCB 15
Portal 14
Theophylline 11
Omeprazole 11
Glutathione 11
Ethanol 9
Domperidone 9
Duloxetine 8
EE2 8
ROS 8
Glycyrrhiza 7
NADH 7
Ginseng 7
Cimetidine 7
Cimetidine 7
more...
Enzyme
CYP3A4 1440
demethylase 141
glutathione S-transferase 116
UDP-glucuronosyltransferase 100
P-glycoprotein 83
NQO1 66
N-acetyltransferase 44
alanine aminotransferase 40
luciferase 39
flavin-containing monooxygenase 39
soluble epoxide hydrolase 38
reverse transcriptase 36
aspartate aminotransferase 33
microsomal epoxide hydrolase 32
6beta-hydroxylase 31
catalase 30
xanthine oxidase 30
superoxide dismutase 26
acetylcholinesterase 22
CPR 18
more...
Compound
caffeine 380
Dec 318
DNA 305
Clin 271
NADPH 239
NADPH 239
Diabetol 166
pyrene 151
water 109
pyridine 79
UDP 73
quinoline 64
quinoline 64
GSH 63
GSH 63
aflatoxin B1 60
ethanol 57
oxygen 56
TCDD 42
uridine 41
more...