Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: HUMANGGP:040116 (histone)
44,835 document(s) hit in 31,850,051 MEDLINE articles (0.03 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
histone 44835
Mol 5882
histone H3 4430
histone deacetylase 3841
Sep 2729
H2A 2052
H2B 1766
methyltransferase 1304
histone H4 1300
ATP 1229
histone acetyltransferase 1192
H2AX 1173
p53 1172
RNA polymerase II 1055
p300 978
HDAC1 906
histone methyltransferase 718
histone H1 680
telomeric 676
HDAC 655
thymus 629
cytokine 617
p21 557
DNA methyltransferase 537
CBP 519
ubiquitin 518
Histone deacetylase 505
histone H2A 505
EZH2 493
SET 474
insulin 467
HDAC2 465
NAD 446
acetyltransferase 442
Pol 410
SWI 397
DNase I 394
DNMT1 373
caspase-3 371
histone H2B 368
more...
Disease
cancer 7022
tumor 3710
tumorigenesis 1167
breast cancer 984
carcinogenesis 960
leukemia 836
diabetes 495
prostate cancer 486
systemic lupus erythematosus 475
tumor progression 474
hepatocellular carcinoma 469
acute myeloid leukemia 413
carcinoma 396
ATM 377
tumor growth 361
lung cancer 330
obesity 329
Alzheimer's disease 322
colorectal cancer 298
cold 277
colon cancer 256
HIV 255
glioma 250
lupus 248
SDS 243
MCF 240
melanoma 229
lymphoma 228
lupus 225
adenocarcinoma 196
multiple myeloma 193
HP1 192
gastric cancer 187
glioblastoma 178
retinoblastoma 175
autoimmune disease 174
rheumatoid arthritis 170
type 2 diabetes 169
hypertension 167
squamous cell carcinoma 165
more...
Symptom
starvation 134
pain 89
seizures 77
ataxia 34
collapse 33
fatigue 26
functional recovery 24
exhaustion 23
diarrhea 17
weakness 15
hypotonia 15
splenomegaly 14
anesthesia 14
memory loss 13
hyperoxia 11
nausea 11
arthralgia 10
HSA 9
respiratory distress 9
Neuropathic pain 8
overweight 8
acute stress 8
hypothermia 7
masculinization 7
vomiting 7
skin damage 6
dyspnea 6
cachexia 5
hunger 5
CSR 5
Ill 5
analgesia 5
chills 4
neurological disability 4
anorexia 4
despair 4
insomnia 4
chorea 4
tremor 4
autodigestion 3
more...
Drug
lysine 6253
DNase I 396
Gel 103
ROS 102
Dermatol 88
Vorinostat 84
MOF 66
IL-2 66
IFN-gamma 64
ascorbate 55
caffeine 53
Cardiovasc 47
ETS 46
NADH 45
Mutagen 43
CSF 40
Ethanol 33
MAP 32
Leaf 30
Romidepsin 30
Biopolymers 28
Asthma 28
Retinoic acid 27
CaCl2 26
CaCl2 25
CaCl2 25
FAD 22
GEO 22
p75 22
Asn 21
Fraction 18
ENT 17
Estrogens 16
VCR 16
BLM 15
Adriamycin 15
ICI 14
CDP 13
Monit 13
Alliance 12
more...
Enzyme
RNA polymerase 1451
histone acetyltransferase 1288
protein kinase 1230
demethylase 890
mitogen-activated protein kinase 607
DNA methyltransferase 550
ERK 550
protein kinase C 468
histone demethylase 455
micrococcal nuclease 393
ATPase 340
proteasome 299
luciferase 284
caspase-3 276
PARP 269
trypsin 250
DNase 233
calcineurin 210
topoisomerase 195
topoisomerase 189
focal adhesion kinase 186
cdc2 185
endonuclease 172
AMPK 171
ACS 164
TSA 143
PHD 133
peroxidase 128
Lys4 118
glutathione S-transferase 114
catalase 104
MEK 102
superoxide dismutase 96
DNA polymerase 95
AMP-activated protein kinase 95
alkaline phosphatase 95
RNase 94
phosphorylase 89
lysozyme 84
GSK 82
more...
Compound
DNA 19476
lysine 6776
Dec 2939
Histone 2893
ATP 1230
arginine 1108
sodium 954
oxygen 809
calcium 754
serine 737
Clin 683
salt 641
phosphate 615
glucose 593
NAD 558
SET 474
acetate 453
cAMP 451
NAD 446
tyrosine 411
urea 392
water 386
zinc 378
sulfate 373
threonine 373
ADP 346
ADP 337
ADP 337
AMP 337
methionine 323
retinoic acid 275
hydrogen 268
SDS 264
cysteine 245
adenosylmethionine 235
ADP-ribose 233
DEAE 233
2-oxoglutarate 226
alanine 223
Mg2+ 223
more...