Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: HUMANGGP:039052 (
PTEN
)
8,951
document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
PTEN
8951
PI3K
1738
AKT
1635
p53
1523
phosphatase
1022
mTOR
945
Mol
899
PIK3CA
615
Sep
520
EGFR
498
BRAF
430
phosphatase and tensin homolog
385
KRAS
370
phosphatidylinositol 3-kinase
321
MAPK
289
insulin
272
phosphoinositide 3-kinase
269
ERK
257
tensin
252
caspase-3
248
more...
Disease
tumor
3777
cancer
3707
breast cancer
793
tumorigenesis
717
prostate cancer
684
carcinoma
492
carcinogenesis
394
tumor growth
391
glioblastoma
391
endometrial cancer
319
Parkinson's disease
315
tumor progression
304
melanoma
293
glioma
290
colorectal cancer
255
metastases
253
Cowden syndrome
233
adenocarcinoma
226
hepatocellular carcinoma
220
lung cancer
208
more...
Symptom
starvation
40
functional recovery
37
seizures
30
diarrhea
14
pain
14
fatigue
13
ataxia
13
collapse
10
nausea
9
hyperoxia
6
exhaustion
6
tremor
6
bradykinesia
5
anesthesia
5
abdominal pain
5
vomiting
5
headache
5
weakness
5
respiratory distress
4
splenomegaly
4
more...
Drug
Parkin
184
Parkin
184
ROS
81
Dermatol
45
lysine
40
ETS
37
Herceptin
33
Monit
25
NVP
24
MAP
20
Cetuximab
20
IL-2
12
PTC
12
Paraffin
11
Gefitinib
11
CSF
10
GEO
9
Cardiovasc
9
ADR
8
Erlotinib
8
more...
Enzyme
ERK
1255
mitogen-activated protein kinase
538
focal adhesion kinase
393
phosphatidylinositol 3-kinase
322
phosphoinositide 3-kinase
269
protein kinase
245
luciferase
217
MEK
202
caspase-3
175
calcineurin
145
APC
136
GSK
120
PARP
110
proteasome
96
PDK1
95
AMP-activated protein kinase
83
STK11
79
AMPK
64
AMPK
64
protein kinase C
60
more...
Compound
DNA
962
Dec
561
Clin
273
oxygen
264
tyrosine
203
glucose
197
MEK
174
MTT
144
methionine
133
serine
125
threonine
124
ATP
114
phosphate
109
MDA
102
TNF
74
calcium
69
Phosphatidylinositol
58
urea
54
TNM
51
lysine
51
more...