Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: HUMANGGP:030881 (JAK1)
 1,750 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
JAK1 1750
JAK2 700
STAT3 477
STAT 428
cytokine 350
STAT1 347
JAK3 320
Janus kinase 249
interferon 166
TYK2 164
IL-6 155
STAT5 144
IFN 144
Mol 139
tyrosine kinase 135
Sep 109
IL-4 86
STAT6 72
interleukin-6 66
TNF 61
more...
Disease
cancer 356
tumor 229
myelofibrosis 133
leukemia 98
rheumatoid arthritis 96
polycythemia vera 70
breast cancer 53
tumor growth 48
anemia 48
myeloproliferative disorders 48
tumorigenesis 47
lymphoma 42
Leukemia 40
essential thrombocythemia 39
hepatocellular carcinoma 37
acute lymphoblastic leukemia 36
arthritis 36
multiple myeloma 33
thrombocytopenia 33
melanoma 32
more...
Symptom
splenomegaly 71
fatigue 14
diarrhea 8
respiratory distress 6
hepatosplenomegaly 5
headache 5
night sweats 5
nausea 5
anorexia 4
pain 4
starvation 3
abdominal discomfort 2
collapse 2
cough 2
abdominal pain 2
dizziness 2
hepatomegaly 1
exhaustion 1
arthralgia 1
sleepiness 1
more...
Drug
IL-2 58
IFN-gamma 49
CSF 18
Dermatol 16
ROS 7
Gel 7
IL-11 7
lysine 6
IFN-beta 6
G-CSF 5
CIA 4
MAP 4
Asthma 3
Vorinostat 2
CCL 2
MRC 2
TEL 2
Myricetin 2
Cardiovasc 2
ABC 2
more...
Enzyme
focal adhesion kinase 1669
mitogen-activated protein kinase 134
ERK 131
caspase-3 37
luciferase 34
MEK 34
protein kinase 29
proteasome 22
protein kinase C 19
phosphatidylinositol 3-kinase 17
PARP 14
IKK 11
collagenase 9
ACS 9
glutathione S-transferase 9
APC 8
catalase 7
superoxide dismutase 7
GAS 7
caspase-8 6
more...
Compound
tyrosine 362
DNA 170
Dec 109
Clin 63
TNF 61
ATP 40
oxygen 39
serine 31
MEK 19
glucose 18
ABL 17
BCR 16
cysteine 14
nitric oxide 14
MTT 13
Tyrosine 12
calcium 12
water 12
arginine 12
MDA 12
more...