Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound   Target Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound

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Query: HUMANGGP:030445 (RAF)
1,929 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .

Human Gene/Protein RAF 1929 MEK 900 ERK 755 BRAF 661 MAPK 392 AKT 301 PI3K 263 KRAS 259 Mol 198 mTOR 179 ERK1 143 Raf-1 135 Sep 125 MEK1 120 NRAS 120 extracellular signal-regulated kinase 106 EGFR 104 B-RAF 96 epidermal growth factor receptor 86 p53 82 more...

Disease cancer 849 tumor 545 melanoma 365 tumorigenesis 133 colorectal cancer 128 tumor growth 99 carcinoma 82 lung cancer 75 hepatocellular carcinoma 71 metastatic melanoma 67 carcinogenesis 55 Melanoma 54 breast cancer 52 sarcoma 50 adenocarcinoma 49 tumor progression 48 leukemia 48 metastases 45 non-small cell lung cancer 45 pancreatic cancer 34 more...

Symptom diarrhea 12 fatigue 11 nausea 7 pain 4 starvation 3 splenomegaly 2 dental pain 2 seizures 2 exhaustion 1 shoulder pain 1 hypothermia 1 numbness 1 vomiting 1 hyperoxia 1 decreased appetite 1 anesthesia 1 flushing 1 orofacial pain 1 weakness 1 Scratch 1 more...

Drug Sorafenib 63 Dermatol 37 MAP 31 Nexavar 14 lysine 9 RAL 8 Cetuximab 8 Imatinib 7 PTC 7 ROS 7 TAK 6 ETS 6 NVP 6 CSF 5 Gleevec 5 Dasatinib 5 Cardiovasc 4 Bayer 4 FLP 4 ABC 3 more...

Enzyme MEK 969 ERK 938 mitogen-activated protein kinase 748 protein kinase 124 focal adhesion kinase 64 phosphatidylinositol 3-kinase 37 protein kinase C 33 MAP 30 phosphoinositide 3-kinase 20 MEKK1 20 PARP 20 caspase-3 17 APC 17 proteasome 17 luciferase 14 PDK1 12 RNA polymerase 11 AMP-activated protein kinase 11 ACS 9 ATPase 8 more...

Compound MEK 890 DNA 131 Dec 130 tyrosine 102 Clin 89 ATP 61 serine 58 threonine 46 GTP 45 methionine 39 MAP 30 oxygen 25 urea 21 ABL 19 BCR 15 cAMP 15 MTT 13 glucose 13 lysine 12 arginine 10 more...

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