Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: HUMANGGP:030395 (APP)
4,616 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
APP 4616
PS1 1430
amyloid precursor protein 1069
Mol 408
BACE1 321
amyloid beta 277
Sep 269
PSEN1 198
axonal 174
precursor protein 148
tau protein 146
CA1 138
presenilin 1 134
PSEN2 128
insulin 119
APOE 105
BACE 89
brain-derived neurotrophic factor 87
TNF 87
cytokine 82
more...
Disease
Alzheimer's disease 3391
plaque 569
dementia 402
cognitive impairment 298
amyloidosis 132
memory impairment 119
neuroblastoma 111
Down syndrome 105
cancer 74
vascular disease 74
Parkinson's disease 72
diabetes 56
depression 43
type 2 diabetes 40
ischemia 39
tumor 37
stroke 33
amyotrophic lateral sclerosis 28
SDS 27
GSH 24
more...
Symptom
memory loss 61
seizures 34
anesthesia 11
pain 8
hypothermia 8
tremor 6
thinning 6
agitation 5
fatigue 5
paraparesis 5
myoclonus 5
ataxia 5
overweight 4
functional recovery 4
starvation 4
forgetfulness 3
nausea and vomiting 3
dystonia 2
hyperoxia 2
exhaustion 2
more...
Drug
CSF 40
ROS 33
FAD 28
p75 20
lysine 15
Parkin 13
ascorbate 13
Parkin 13
Donepezil 12
Glucagon 9
MAP 8
Monit 8
DPA 7
vitamin E 6
Asn 6
Gel 6
Cardiovasc 5
Frontal 4
Leaf 4
caffeine 4
more...
Enzyme
mitogen-activated protein kinase 129
protein kinase 101
beta-secretase 89
ERK 87
acetylcholinesterase 65
caspase-3 63
CD10 61
protein kinase C 56
GSK 51
superoxide dismutase 46
ACS 43
proteasome 41
insulin-degrading enzyme 40
Thy1 35
cholinesterase 30
luciferase 28
AMP-activated protein kinase 28
cathepsin D 21
ATPase 21
AMPK 21
more...
Compound
water 346
Dec 300
DNA 188
calcium 125
oxygen 121
glucose 113
TNF 87
glutamate 84
ATP 62
Clin 58
iron 57
phosphate 56
nitric oxide 44
ACS 43
ACS 43
hydrogen 41
copper 40
sodium 37
tyrosine 36
zinc 35
more...