Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: HUMANGGP:030395 (
APP
)
4,616
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
APP
4616
PS1
1430
amyloid precursor protein
1069
Mol
408
BACE1
321
amyloid beta
277
Sep
269
PSEN1
198
axonal
174
precursor protein
148
tau protein
146
CA1
138
presenilin 1
134
PSEN2
128
insulin
119
APOE
105
BACE
89
brain-derived neurotrophic factor
87
TNF
87
cytokine
82
more...
Disease
Alzheimer's disease
3391
plaque
569
dementia
402
cognitive impairment
298
amyloidosis
132
memory impairment
119
neuroblastoma
111
Down syndrome
105
cancer
74
vascular disease
74
Parkinson's disease
72
diabetes
56
depression
43
type 2 diabetes
40
ischemia
39
tumor
37
stroke
33
amyotrophic lateral sclerosis
28
SDS
27
GSH
24
more...
Symptom
memory loss
61
seizures
34
anesthesia
11
pain
8
hypothermia
8
tremor
6
thinning
6
agitation
5
fatigue
5
paraparesis
5
myoclonus
5
ataxia
5
overweight
4
functional recovery
4
starvation
4
forgetfulness
3
nausea and vomiting
3
dystonia
2
hyperoxia
2
exhaustion
2
more...
Drug
CSF
40
ROS
33
FAD
28
p75
20
lysine
15
Parkin
13
ascorbate
13
Parkin
13
Donepezil
12
Glucagon
9
MAP
8
Monit
8
DPA
7
vitamin E
6
Asn
6
Gel
6
Cardiovasc
5
Frontal
4
Leaf
4
caffeine
4
more...
Enzyme
mitogen-activated protein kinase
129
protein kinase
101
beta-secretase
89
ERK
87
acetylcholinesterase
65
caspase-3
63
CD10
61
protein kinase C
56
GSK
51
superoxide dismutase
46
ACS
43
proteasome
41
insulin-degrading enzyme
40
Thy1
35
cholinesterase
30
luciferase
28
AMP-activated protein kinase
28
cathepsin D
21
ATPase
21
AMPK
21
more...
Compound
water
346
Dec
300
DNA
188
calcium
125
oxygen
121
glucose
113
TNF
87
glutamate
84
ATP
62
Clin
58
iron
57
phosphate
56
nitric oxide
44
ACS
43
ACS
43
hydrogen
41
copper
40
sodium
37
tyrosine
36
zinc
35
more...