Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: HUMANGGP:030133 (IL-1)
 19,225 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
IL-1 19225
cytokine 5448
IL-6 4846
TNF 3463
tumor necrosis factor 2238
TNF-alpha 1849
IL-1 beta 1787
lipopolysaccharide 1700
IL-2 1629
IL-8 1406
IL-10 1385
LPS 1349
IL-4 1281
Sep 1228
IL-1 alpha 1199
IFN-gamma 1085
IFN 965
Cytokine 809
interferon 784
Mol 706
more...
Disease
cancer 965
tumor 953
rheumatoid arthritis 819
arthritis 707
sepsis 383
sepsis 375
diabetes 367
osteoarthritis 316
atherosclerosis 290
asthma 245
leukemia 198
psoriasis 197
ischemia 188
obesity 184
melanoma 184
PHA 181
infectious diseases 167
depression 167
Alzheimer's disease 167
HIV 165
more...
Symptom
pain 254
anorexia 112
cachexia 78
fatigue 68
respiratory distress 66
seizures 58
arthralgia 47
anesthesia 42
diarrhea 34
headache 32
erythema 28
analgesia 25
splenomegaly 23
hypothermia 22
hyperoxia 22
myalgia 22
exhaustion 21
cough 20
collapse 16
weakness 15
more...
Drug
IL-2 1636
IFN-gamma 1065
CSF 741
IL-1ra 381
Dermatol 275
G-CSF 188
IFN-beta 141
IL-11 112
Anakinra 88
ROS 88
p75 57
Indomethacin 53
MAP 50
Gel 49
lysine 45
PTH 43
Asthma 30
Cardiovasc 27
CCL 26
vitamin E 24
more...
Enzyme
mitogen-activated protein kinase 711
caspase-1 421
collagenase 269
protein kinase C 251
ERK 243
protein kinase 227
superoxide dismutase 220
peroxidase 182
catalase 149
IKK 136
caspase-3 134
MIP 132
luciferase 129
NO synthase 121
MMP-3 120
reverse transcriptase 113
phospholipase A2 94
trypsin 93
APC 88
alanine aminotransferase 85
more...
Compound
TNF 3463
Dec 1288
Clin 1147
DNA 825
nitric oxide 540
oxygen 527
calcium 458
PGE2 385
acetate 372
glucose 350
sodium 263
water 221
sulfate 204
cAMP 198
PMA 196
PMA 192
THP 179
THP 178
arginine 166
leucine 161
more...