Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: HUMANGGP:028818 (
TNF-alpha
)
26,445
document(s) hit in 31,850,051 MEDLINE articles (0.03 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
TNF-alpha
26445
cytokine
8517
IL-6
6645
IFN-gamma
5730
tumor necrosis factor
4237
IL-10
3658
LPS
2619
IL-4
2455
IL-2
2209
IL-8
2183
lipopolysaccharide
2100
Sep
1887
IL-1
1849
TNF
1522
IL-1 beta
1437
Mol
1204
Cytokine
1077
TGF-beta
1067
CD4
1018
GM-CSF
987
more...
Disease
tumor
1592
cancer
1472
rheumatoid arthritis
998
sepsis
727
sepsis
709
HIV
633
diabetes
596
arthritis
590
atherosclerosis
451
ischemia
440
tuberculosis
439
Mycobacterium
411
asthma
408
multiple sclerosis
369
Crohn's disease
348
obesity
339
inflammatory bowel disease
318
infectious diseases
315
MIP
309
psoriasis
291
more...
Symptom
pain
198
cachexia
113
anesthesia
83
diarrhea
82
anorexia
60
respiratory distress
60
hypothermia
57
fatigue
54
seizures
38
splenomegaly
33
overweight
31
collapse
31
headache
29
hyperoxia
28
erythema
28
arthralgia
24
starvation
24
weakness
24
dyspnea
22
exhaustion
22
more...
Drug
IFN-gamma
5685
IL-2
2210
CSF
1240
Dermatol
295
p75
236
IFN-beta
231
G-CSF
180
Infliximab
114
Infliximab
114
IL-1ra
111
ROS
109
MAP
93
lysine
71
Monit
68
IL-11
68
Adalimumab
52
vitamin E
48
Asthma
48
Gel
39
Cardiovasc
38
more...
Enzyme
mitogen-activated protein kinase
1286
peroxidase
480
ERK
405
protein kinase C
377
caspase-3
353
protein kinase
324
NO synthase
316
MIP
310
luciferase
246
superoxide dismutase
236
reverse transcriptase
228
alanine aminotransferase
218
IKK
198
catalase
188
collagenase
168
MEK
162
caspase-8
154
APC
149
aspartate aminotransferase
130
NADPH oxidase
129
more...
Compound
Dec
2012
DNA
1677
TNF
1522
Clin
1449
nitric oxide
1235
oxygen
928
calcium
600
glucose
499
acetate
409
THP
394
THP
391
PMA
354
PMA
350
water
344
sodium
335
tyrosine
314
arginine
311
cAMP
302
PGE2
298
PGE
285
more...