Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: HUMANGGP:027779 (leptin)
21,311 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
leptin 21311
insulin 7742
Leptin 5245
adiponectin 3518
leptin receptor 2327
ghrelin 1490
Sep 1367
Mol 1209
resistin 1026
cytokine 970
neuropeptide Y 943
adipokine 941
IL-6 817
tumor necrosis factor 740
TNF 616
growth hormone 542
glucagon 534
beta-endorphin 515
STAT3 502
C-reactive protein 495
more...
Disease
obesity 7858
diabetes 2419
type 2 diabetes 1205
metabolic syndrome 1120
hypertension 893
cancer 859
hyperphagia 610
hyperinsulinemia 570
hyperglycemia 527
cardiovascular disease 520
glucose intolerance 470
tumor 450
fatty liver 438
dyslipidemia 401
breast cancer 393
atherosclerosis 391
malnutrition 260
depression 241
hyperlipidemia 223
anorexia nervosa 221
more...
Symptom
overweight 761
anorexia 351
hunger 255
starvation 250
cachexia 148
fatigue 122
pain 79
hypothermia 38
seizures 30
anesthesia 28
headache 21
acute stress 21
sleepiness 19
decreased appetite 18
exhaustion 16
insomnia 15
hepatomegaly 14
nausea 14
vomiting 12
hypercapnia 11
more...
Drug
IL-2 61
Cardiovasc 54
Growth hormone 44
Growth hormone 44
MAP 42
EE2 41
CSF 37
lysine 35
ROS 34
Dermatol 34
caffeine 33
Glucagon 32
IFN-gamma 32
lactose 30
vitamin E 28
PTH 27
Fructose 25
Monit 24
CTX 24
Orlistat 23
more...
Enzyme
mitogen-activated protein kinase 515
AMP-activated protein kinase 391
focal adhesion kinase 276
protein kinase 260
lipoprotein lipase 226
ERK 200
AMPK 166
AMPK 159
renin 139
alanine aminotransferase 137
phosphatidylinositol 3-kinase 123
superoxide dismutase 116
hormone-sensitive lipase 108
acetyl-CoA carboxylase 105
alkaline phosphatase 101
lipase 99
aspartate aminotransferase 93
CPT 87
catalase 82
phosphoenolpyruvate carboxykinase 80
more...
Compound
glucose 4695
Dec 1506
Clin 1303
Insulin 675
TNF 616
water 540
DNA 483
oxygen 455
calcium 289
tyrosine 277
nitric oxide 257
sodium 184
ATP 178
cAMP 172
glycerol 161
ACTH 159
TSH 156
phosphate 152
urea 150
arginine 139
more...