Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: HUMANGGP:027779 (
leptin
)
21,311
document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
leptin
21311
insulin
7742
Leptin
5245
adiponectin
3518
leptin receptor
2327
ghrelin
1490
Sep
1367
Mol
1209
resistin
1026
cytokine
970
neuropeptide Y
943
adipokine
941
IL-6
817
tumor necrosis factor
740
TNF
616
growth hormone
542
glucagon
534
beta-endorphin
515
STAT3
502
C-reactive protein
495
more...
Disease
obesity
7858
diabetes
2419
type 2 diabetes
1205
metabolic syndrome
1120
hypertension
893
cancer
859
hyperphagia
610
hyperinsulinemia
570
hyperglycemia
527
cardiovascular disease
520
glucose intolerance
470
tumor
450
fatty liver
438
dyslipidemia
401
breast cancer
393
atherosclerosis
391
malnutrition
260
depression
241
hyperlipidemia
223
anorexia nervosa
221
more...
Symptom
overweight
761
anorexia
351
hunger
255
starvation
250
cachexia
148
fatigue
122
pain
79
hypothermia
38
seizures
30
anesthesia
28
headache
21
acute stress
21
sleepiness
19
decreased appetite
18
exhaustion
16
insomnia
15
hepatomegaly
14
nausea
14
vomiting
12
hypercapnia
11
more...
Drug
IL-2
61
Cardiovasc
54
Growth hormone
44
Growth hormone
44
MAP
42
EE2
41
CSF
37
lysine
35
ROS
34
Dermatol
34
caffeine
33
Glucagon
32
IFN-gamma
32
lactose
30
vitamin E
28
PTH
27
Fructose
25
Monit
24
CTX
24
Orlistat
23
more...
Enzyme
mitogen-activated protein kinase
515
AMP-activated protein kinase
391
focal adhesion kinase
276
protein kinase
260
lipoprotein lipase
226
ERK
200
AMPK
166
AMPK
159
renin
139
alanine aminotransferase
137
phosphatidylinositol 3-kinase
123
superoxide dismutase
116
hormone-sensitive lipase
108
acetyl-CoA carboxylase
105
alkaline phosphatase
101
lipase
99
aspartate aminotransferase
93
CPT
87
catalase
82
phosphoenolpyruvate carboxykinase
80
more...
Compound
glucose
4695
Dec
1506
Clin
1303
Insulin
675
TNF
616
water
540
DNA
483
oxygen
455
calcium
289
tyrosine
277
nitric oxide
257
sodium
184
ATP
178
cAMP
172
glycerol
161
ACTH
159
TSH
156
phosphate
152
urea
150
arginine
139
more...