Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: HUMANGGP:027778 (
Leptin
)
5,668
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
Leptin
5668
leptin
5245
insulin
1327
leptin receptor
1104
adiponectin
454
cytokine
376
Mol
355
Sep
341
adipokine
264
STAT3
229
neuropeptide Y
228
ghrelin
178
short form
147
IL-6
140
Adiponectin
139
growth hormone
130
resistin
123
tumor necrosis factor
117
STAT
114
MAPK
110
more...
Disease
obesity
1712
diabetes
481
hypertension
240
cancer
232
type 2 diabetes
174
metabolic syndrome
166
breast cancer
134
tumor
130
hyperinsulinemia
129
hyperphagia
120
cardiovascular disease
104
hyperglycemia
96
atherosclerosis
95
fatty liver
66
carcinogenesis
63
infertility
63
depression
57
malnutrition
54
anorexia nervosa
54
glucose intolerance
52
more...
Symptom
overweight
156
starvation
90
anorexia
79
hunger
41
cachexia
38
fatigue
31
pain
15
hypothermia
11
anesthesia
11
seizures
8
decreased appetite
7
despair
6
exhaustion
6
acute stress
5
hypercapnia
4
respiratory distress
3
agitation
3
emaciation
3
diarrhea
3
weakness
2
more...
Drug
EE2
21
IFN-gamma
17
Growth hormone
17
IL-2
17
Growth hormone
17
MAP
16
ROS
14
Dermatol
13
G-CSF
12
Cardiovasc
12
lysine
11
CSF
11
lactose
9
Dial
8
PTH
7
Portal
7
Glucagon
7
DMI
7
Estrogens
6
caffeine
6
more...
Enzyme
mitogen-activated protein kinase
255
focal adhesion kinase
118
ERK
85
AMP-activated protein kinase
78
protein kinase
72
phosphatidylinositol 3-kinase
63
lipoprotein lipase
37
protein kinase C
34
caspase-3
34
MEK
33
luciferase
31
AMPK
29
AMPK
29
reverse transcriptase
26
alkaline phosphatase
25
NADPH oxidase
22
superoxide dismutase
21
renin
21
phosphoinositide 3-kinase
21
catalase
20
more...
Compound
glucose
799
Dec
402
Clin
371
Insulin
167
DNA
143
oxygen
100
nitric oxide
98
tyrosine
94
TNF
85
water
83
calcium
70
cAMP
68
sodium
56
ACTH
55
arginine
50
phosphate
49
TSH
47
ATP
41
creatinine
37
glutamate
33
more...