Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: HUMANGGP:027778 (Leptin)
5,668 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
Leptin 5668
leptin 5245
insulin 1327
leptin receptor 1104
adiponectin 454
cytokine 376
Mol 355
Sep 341
adipokine 264
STAT3 229
neuropeptide Y 228
ghrelin 178
short form 147
IL-6 140
Adiponectin 139
growth hormone 130
resistin 123
tumor necrosis factor 117
STAT 114
MAPK 110
more...
Disease
obesity 1712
diabetes 481
hypertension 240
cancer 232
type 2 diabetes 174
metabolic syndrome 166
breast cancer 134
tumor 130
hyperinsulinemia 129
hyperphagia 120
cardiovascular disease 104
hyperglycemia 96
atherosclerosis 95
fatty liver 66
carcinogenesis 63
infertility 63
depression 57
malnutrition 54
anorexia nervosa 54
glucose intolerance 52
more...
Symptom
overweight 156
starvation 90
anorexia 79
hunger 41
cachexia 38
fatigue 31
pain 15
hypothermia 11
anesthesia 11
seizures 8
decreased appetite 7
despair 6
exhaustion 6
acute stress 5
hypercapnia 4
respiratory distress 3
agitation 3
emaciation 3
diarrhea 3
weakness 2
more...
Drug
EE2 21
IFN-gamma 17
Growth hormone 17
IL-2 17
Growth hormone 17
MAP 16
ROS 14
Dermatol 13
G-CSF 12
Cardiovasc 12
lysine 11
CSF 11
lactose 9
Dial 8
PTH 7
Portal 7
Glucagon 7
DMI 7
Estrogens 6
caffeine 6
more...
Enzyme
mitogen-activated protein kinase 255
focal adhesion kinase 118
ERK 85
AMP-activated protein kinase 78
protein kinase 72
phosphatidylinositol 3-kinase 63
lipoprotein lipase 37
protein kinase C 34
caspase-3 34
MEK 33
luciferase 31
AMPK 29
AMPK 29
reverse transcriptase 26
alkaline phosphatase 25
NADPH oxidase 22
superoxide dismutase 21
renin 21
phosphoinositide 3-kinase 21
catalase 20
more...
Compound
glucose 799
Dec 402
Clin 371
Insulin 167
DNA 143
oxygen 100
nitric oxide 98
tyrosine 94
TNF 85
water 83
calcium 70
cAMP 68
sodium 56
ACTH 55
arginine 50
phosphate 49
TSH 47
ATP 41
creatinine 37
glutamate 33
more...