Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: HUMANGGP:027313 (JAK2)
 5,448 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
JAK2 5448
STAT3 1480
STAT 805
JAK1 700
cytokine 666
STAT5 531
tyrosine kinase 518
Janus kinase 471
Mol 463
MPL 394
STAT1 374
Sep 342
IL-6 321
Calreticulin 271
JAK3 263
erythroid 224
erythropoietin 205
MAPK 199
PI3K 195
interferon 186
more...
Disease
cancer 1058
polycythemia vera 719
myeloproliferative disorders 696
essential thrombocythemia 639
tumor 592
primary myelofibrosis 490
myelofibrosis 460
leukemia 379
thrombocytosis 254
acute myeloid leukemia 228
chronic myeloid leukemia 198
anemia 177
myelodysplastic syndrome 168
ABL 158
lymphoma 156
tumor growth 140
Leukemia 137
breast cancer 125
erythrocytosis 122
obesity 118
more...
Symptom
splenomegaly 236
pain 27
fatigue 24
hepatosplenomegaly 18
headache 17
night sweats 9
functional recovery 9
starvation 8
diarrhea 8
abdominal pain 8
cachexia 7
dizziness 6
seizures 6
overweight 6
anorexia 5
vomiting 5
respiratory distress 5
collapse 4
hepatomegaly 4
nausea 4
more...
Drug
CSF 65
IFN-gamma 53
Growth hormone 52
Growth hormone 52
TEL 45
ROS 39
MDS 38
IL-2 34
MAP 24
Imatinib 17
lysine 17
Monit 16
Dermatol 16
Angiotensin II 14
G-CSF 13
IL-11 10
Gel 9
Vitamin A 8
NVP 8
Cardiovasc 6
more...
Enzyme
focal adhesion kinase 5448
mitogen-activated protein kinase 493
ERK 481
MEK 125
protein kinase 105
caspase-3 94
luciferase 93
protein kinase C 64
phosphatidylinositol 3-kinase 62
PARP 39
superoxide dismutase 34
lactate dehydrogenase 33
AMP-activated protein kinase 31
proteasome 29
AMPK 24
MAP 22
AMPK 22
GAS 21
glutathione S-transferase 21
IKK 20
more...
Compound
tyrosine 767
DNA 444
Dec 362
Clin 218
BCR 165
oxygen 161
ABL 158
TNF 141
glucose 109
MEK 84
serine 83
ATP 72
nitric oxide 56
calcium 56
MTT 52
MDA 46
TEL 45
Tyrosine 41
Phe 41
water 38
more...