Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: HUMANGGP:026598 (
epidermal growth factor receptor
)
23,623
document(s) hit in 31,850,051 MEDLINE articles (0.02 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
epidermal growth factor receptor
23623
tyrosine kinase
4460
Mol
2064
EGF
1824
EGFR
1639
HER2
1626
Sep
1568
estrogen receptor
1375
epidermal growth factor
1218
progesterone receptor
1008
p53
913
vascular endothelial growth factor
816
AKT
812
KRAS
656
ERK
636
receptor tyrosine kinase
630
ERK1
621
mTOR
565
MAPK
518
erbB-2
510
more...
Disease
cancer
8819
tumor
7167
breast cancer
4171
lung cancer
2431
non-small cell lung cancer
2203
adenocarcinoma
1459
carcinoma
1405
colorectal cancer
1139
metastases
1097
squamous cell carcinoma
1005
tumor growth
969
tumorigenesis
812
carcinogenesis
651
tumor progression
641
lung carcinoma
636
metastatic breast cancer
535
glioblastoma
524
glioma
503
gastric cancer
449
MCF
392
more...
Symptom
diarrhea
234
pain
75
fatigue
74
nausea
64
dyspnea
46
starvation
35
cough
32
vomiting
31
anorexia
23
headache
22
dry skin
22
discomfort
21
discomfort
21
erythema
21
functional recovery
16
abdominal pain
14
asthenia
11
shortness of breath
11
hemoptysis
10
respiratory distress
10
more...
Drug
Gefitinib
631
Herceptin
521
Cetuximab
451
Erlotinib
381
Dermatol
195
Tarceva
122
DM1
102
Bevacizumab
88
lysine
79
Panitumumab
69
MAP
67
ROS
55
Docetaxel
45
Taxol
38
Cardiovasc
37
Pertuzumab
37
Paraffin
33
Vandetanib
29
CSF
29
Pemetrexed
29
more...
Enzyme
ERK
4537
mitogen-activated protein kinase
2080
protein kinase
597
MEK
492
focal adhesion kinase
381
protein kinase C
378
phosphatidylinositol 3-kinase
326
phosphoinositide 3-kinase
180
caspase-3
163
luciferase
154
phospholipase C
142
PARP
116
ACS
114
proteasome
100
ATPase
80
reverse transcriptase
72
NADPH oxidase
70
urokinase-type plasminogen activator
58
NADPH oxidase
56
P-glycoprotein
53
more...
Compound
tyrosine
2134
DNA
1734
Dec
1603
Clin
1423
methionine
490
MDA
489
oxygen
406
MEK
339
calcium
324
ATP
321
serine
246
MTT
221
threonine
219
cysteine
184
glucose
179
phosphate
173
water
164
acetate
154
PEG
153
Cbl
141
more...