Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: HUMANGGP:023882 (extracellular signal-regulated kinase)
 12,069 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
extracellular signal-regulated kinase 12069
p38 2331
ERK1 1929
Mol 1581
mitogen-activated protein 1332
MEK 1148
ERK 1002
c-Jun 984
MAPK 931
Sep 844
p38 mitogen-activated protein kinase 672
tumor necrosis factor 658
cytokine 634
phosphatidylinositol 3-kinase 597
AKT 562
lipopolysaccharide 516
caspase-3 511
protein kinase B 464
ERK2 457
MEK1 452
more...
Disease
cancer 1955
tumor 1286
breast cancer 318
tumor growth 306
tumorigenesis 278
melanoma 274
carcinogenesis 259
carcinoma 215
hepatocellular carcinoma 214
leukemia 212
ischemia 209
diabetes 191
atherosclerosis 185
lung cancer 179
pertussis 176
Alzheimer's disease 168
hypertension 163
tumor progression 158
depression 131
colon cancer 131
more...
Symptom
pain 235
starvation 32
seizures 21
functional recovery 19
collapse 19
diarrhea 17
anesthesia 17
hyperoxia 15
analgesia 14
hypothermia 11
thinning 8
headache 8
despair 7
fatigue 7
respiratory distress 7
orofacial pain 7
memory loss 6
erythema 6
splenomegaly 6
acute stress 5
more...
Drug
Dermatol 139
MAP 136
Angiotensin II 68
IFN-gamma 64
ROS 58
CSF 52
IL-2 49
lysine 40
ICI 40
Sorafenib 36
Cardiovasc 33
Gefitinib 20
vitamin E 18
Ethanol 15
Forskolin 15
Taxol 15
caffeine 15
p75 15
ETS 14
Arsenic trioxide 13
more...
Enzyme
mitogen-activated protein kinase 12069
MEK 1837
ERK 1350
protein kinase 1307
protein kinase C 818
phosphatidylinositol 3-kinase 597
caspase-3 441
focal adhesion kinase 427
phosphoinositide 3-kinase 292
luciferase 231
phospholipase C 195
calcineurin 129
MAP 129
NO synthase 129
NADPH oxidase 126
PARP 122
superoxide dismutase 116
NADPH oxidase 110
MEKK1 105
catalase 100
more...
Compound
MEK 1084
DNA 945
Dec 879
oxygen 838
tyrosine 718
calcium 607
nitric oxide 403
cAMP 351
acetate 349
TNF 324
NH2 313
glucose 312
serine 308
threonine 233
glutamate 193
sodium 186
water 184
Clin 182
MTT 168
cysteine 164
more...