Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: HUMANGGP:023881 (MEK1)
 4,168 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
MEK1 4168
ERK1 1658
ERK 1109
MEK 1004
MAPK 936
p38 729
Mol 512
extracellular signal-regulated kinase 452
JNK 380
ERK2 367
mitogen-activated protein 353
BRAF 319
MAP kinase 297
Sep 295
PI3K 294
MEK2 276
Raf-1 250
c-Jun 231
AKT 190
cytokine 187
more...
Disease
cancer 756
tumor 520
melanoma 156
breast cancer 154
tumorigenesis 133
tumor growth 130
leukemia 110
carcinoma 97
hepatocellular carcinoma 80
carcinogenesis 76
lung cancer 64
ischemia 63
MCF 63
pertussis 62
tumor progression 59
colorectal cancer 57
adenocarcinoma 55
colon cancer 54
atherosclerosis 53
prostate cancer 53
more...
Symptom
starvation 15
pain 12
diarrhea 8
nausea 7
fatigue 7
seizures 6
collapse 5
hypotonia 5
functional recovery 5
cachexia 4
weakness 4
respiratory distress 4
analgesia 3
exhaustion 3
memory loss 2
Neuropathic pain 2
anesthesia 2
Organ failure 1
ENT 1
arthralgia 1
more...
Drug
MAP 120
ROS 35
CSF 25
Dermatol 19
IL-2 16
IFN-gamma 16
ICI 15
lysine 14
Sorafenib 13
Gel 12
Angiotensin II 12
Taxol 11
Gefitinib 9
ETS 9
ascorbate 9
caffeine 8
Monit 7
Imatinib 7
TAK 6
Ouabain 5
more...
Enzyme
MEK 4168
mitogen-activated protein kinase 3063
ERK 1313
protein kinase 614
protein kinase C 350
phosphatidylinositol 3-kinase 166
focal adhesion kinase 163
luciferase 117
MAP 117
MEKK1 93
caspase-3 89
calcineurin 62
phospholipase C 51
phosphoinositide 3-kinase 50
NADPH oxidase 46
NADPH oxidase 40
proteasome 40
GSK 40
IKK 39
cdc2 36
more...
Compound
MEK 937
DNA 360
Dec 323
tyrosine 264
oxygen 175
serine 169
calcium 166
threonine 141
acetate 138
MAP 117
ATP 103
cAMP 84
glucose 82
TNF 76
nitric oxide 75
MDA 68
sodium 63
Clin 58
hydrogen 49
alanine 48
more...