Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: HUMANGGP:023640 (COX-2)
 12,853 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
COX-2 12853
cyclooxygenase 3867
COX-1 3497
inducible nitric oxide synthase 1994
TNF 1506
IL-6 1409
lipopolysaccharide 1105
Sep 847
COX 791
LPS 765
Mol 743
cytokine 688
p38 647
p65 543
MAPK 491
tumor necrosis factor 468
caspase-3 392
cyclooxygenase-2 392
ERK 363
JNK 362
more...
Disease
cancer 2048
tumor 1353
carcinogenesis 667
colon cancer 380
colorectal cancer 377
osteoarthritis 354
arthritis 339
tumorigenesis 336
tumor growth 307
rheumatoid arthritis 301
breast cancer 293
carcinoma 268
Alzheimer's disease 264
colitis 210
GSH 203
hypertension 202
ischemia 200
diabetes 199
adenocarcinoma 188
lung cancer 167
more...
Symptom
pain 849
analgesia 100
seizures 66
acute pain 53
diarrhea 48
anesthesia 47
headache 29
erythema 28
arthralgia 19
anorexia 19
skin damage 18
hypothermia 17
nausea 17
cachexia 15
vomiting 15
dental pain 15
abdominal pain 14
low back pain 13
fatigue 11
functional recovery 10
more...
Drug
ROS 215
Indomethacin 178
IFN-gamma 69
MAP 63
IL-2 62
Nimesulide 61
Dermatol 52
Vioxx 48
CSF 44
Cardiovasc 39
Celebrex 38
vitamin E 33
Valdecoxib 29
lysine 28
ascorbate 28
EPA 25
Glycyrrhiza 24
Monit 23
Parecoxib 21
Asthma 16
more...
Enzyme
mitogen-activated protein kinase 1080
ERK 537
superoxide dismutase 331
caspase-3 319
peroxidase 305
catalase 216
phospholipase A2 215
protein kinase 201
protein kinase C 197
NO synthase 182
lipoxygenase 179
luciferase 149
prostaglandin synthetase 135
MEK 133
NOS 129
alanine aminotransferase 114
collagenase 114
IKK 112
PARP 108
focal adhesion kinase 103
more...
Compound
TNF 1506
PGE 1395
PGE2 1162
Dec 943
nitric oxide 921
COX 791
DNA 577
oxygen 537
Clin 490
sodium 409
water 409
prostacyclin 393
Celecoxib 265
calcium 253
acetate 242
ASA 214
ethanol 208
arginine 207
GSH 205
GSH 205
more...