Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: HUMANGGP:022417 (MDR1)
 3,915 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
MDR1 3915
P-glycoprotein 1886
ABCB1 484
P-gp 398
MRP1 334
ATP 313
Mol 294
Sep 254
BCRP 248
MRP2 235
ATP-binding cassette 202
ABCG2 178
ATPase 168
ABC 146
MRP 131
CYP3A4 126
breast cancer resistance protein 125
p53 119
ABCC1 114
mdr1 111
more...
Disease
cancer 1242
tumor 680
leukemia 196
breast cancer 189
carcinoma 165
acute myeloid leukemia 143
MCF 133
lymphoma 95
hepatocellular carcinoma 84
ovarian cancer 79
HIV 70
adenocarcinoma 67
tumor growth 66
lung cancer 63
chronic myeloid leukemia 57
acute lymphoblastic leukemia 56
multiple myeloma 55
CEM 54
colorectal cancer 47
epilepsy 44
more...
Symptom
seizures 19
pain 14
diarrhea 7
starvation 6
nausea 6
ataxia 5
angina 5
vomiting 3
lethargy 3
fatigue 2
myalgia 2
agitation 2
tremor 2
cancer pain 2
dizziness 2
colic 1
breakthrough pain 1
adenitis 1
asthenia 1
polydipsia 1
more...
Drug
ABC 146
ADR 70
ADM 45
Adriamycin 45
VCR 28
VCR 28
Taxol 23
Imatinib 17
Fluconazole 17
ROS 16
Monit 15
Gleevec 12
lysine 10
G418 10
CPT-11 9
CSF 8
Docetaxel 8
Irinotecan 7
DM1 7
Glutathione 6
more...
Enzyme
P-glycoprotein 1890
MDR 231
ATPase 171
CYP3A4 126
ERK 88
glutathione S-transferase 75
topoisomerase 71
topoisomerase 60
reverse transcriptase 59
caspase-3 56
mitogen-activated protein kinase 49
protein kinase C 47
luciferase 44
RNA polymerase 32
protein kinase 31
focal adhesion kinase 24
catalase 22
transcriptase 17
caspase-9 16
dihydrofolate reductase 15
more...
Compound
DNA 371
ATP 313
Dec 285
MDR 231
Clin 176
MTT 130
ADR 104
Adriamycin 79
sodium 55
Verapamil 52
Verapamil 52
DDP 51
Rhodamine 123 50
MDA 41
calcium 41
GSH 35
GSH 35
oxygen 35
water 33
glucose 32
more...