Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: HUMANGGP:021790 (frataxin)
 1,370 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
frataxin 1370
GAA 336
Mol 175
Frataxin 172
FRDA 99
Sep 90
aconitase 86
ferritin 46
cysteine desulfurase 45
ATP 40
IscU 33
ferredoxin 31
axonal 27
ISCU 26
NFS1 26
ferrochelatase 24
ISD11 22
NMR 21
histone 21
insulin 19
more...
Disease
Friedreich's ataxia 1111
cardiomyopathy 146
diabetes 71
hypertrophic cardiomyopathy 60
FRDA 57
iron overload 49
Huntington's disease 39
Alzheimer's disease 37
Cerebellum 35
neuropathy 34
hereditary ataxia 34
Parkinson's disease 30
vitamin E deficiency 28
mitochondrial disease 27
heart failure 27
scoliosis 27
degenerative disease 24
amyotrophic lateral sclerosis 23
cancer 23
DM1 21
more...
Symptom
ataxia 303
cerebellar ataxia 48
dysarthria 46
weakness 25
tremor 14
spasticity 10
dystonia 7
ataxic gait 7
incoordination 5
starvation 5
ophthalmoplegia 5
pain 4
chorea 4
hypotonia 4
neurological disability 4
abnormal gait 3
thinning 3
pallor 3
hyperoxia 3
anesthesia 3
more...
Drug
TTC 30
vitamin E 20
Idebenone 11
NADH 10
ROS 9
lysine 8
Vitamin E 7
EPI 4
Gel 3
ADM 3
TAT 3
CTT 3
Cardiovasc 3
pyridoxal phosphate 2
DNase I 2
citric acid 2
Glutathione 2
IL-2 1
Asthma 1
ZnCl2 1
more...
Enzyme
aconitase 86
IscS 57
succinate dehydrogenase 30
ferrochelatase 24
superoxide dismutase 17
complex I 12
MPP 11
ceruloplasmin 9
RNA polymerase 9
citrate synthase 8
glutathione peroxidase 8
cytochrome oxidase 8
catalase 7
pyruvate dehydrogenase 7
proteasome 6
pyruvate dehydrogenase 5
protein kinase 5
diaphorase 5
pyruvate dehydrogenase 5
ACS 4
more...
Compound
iron 544
DNA 199
oxygen 94
Dec 91
Clin 42
cysteine 40
ATP 40
TTC 30
hydrogen 27
glucose 26
calcium 19
zinc 17
Cardiol 15
coenzyme Q10 15
water 13
His 11
copper 11
NADH 10
phosphate 10
GSH 10
more...