Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: HUMANGGP:021468 (PS1)
 2,734 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
PS1 2734
APP 1430
amyloid precursor protein 620
PS2 413
Mol 225
amyloid beta 166
Sep 158
presenilin 1 153
BACE1 114
endoplasmic reticulum 92
nicastrin 87
CA1 75
PS-2 74
insulin 66
brain-derived neurotrophic factor 58
precursor protein 55
TNF 51
cytokine 46
tau protein 44
synaptophysin 44
more...
Disease
Alzheimer's disease 2081
plaque 371
cognitive impairment 208
dementia 202
amyloidosis 87
memory impairment 82
neuroblastoma 59
cancer 40
familial Alzheimer disease 34
type 2 diabetes 32
diabetes 30
depression 27
tumor 24
vascular disease 22
Parkinson's disease 22
SDS 19
brain atrophy 16
Down syndrome 15
GSH 14
cognitive deficit 13
more...
Symptom
memory loss 47
seizures 10
pain 5
apathy 4
agitation 4
anesthesia 4
fatigue 3
functional recovery 3
hypercapnia 3
paraparesis 3
overweight 3
thinning 2
syncope 2
nausea and vomiting 2
hyperoxia 2
hypothermia 2
collapse 2
myoclonus 1
diarrhea 1
weakness 1
more...
Drug
FAD 34
ROS 17
p75 15
CSF 15
lysine 10
Glucagon 8
Donepezil 6
Parkin 6
Parkin 6
DPA 5
NADH 5
caffeine 4
Portal 4
Epigallocatechin 4
ascorbate 3
Leaf 3
uPA 3
citric acid 3
Liraglutide 3
Safflower 3
more...
Enzyme
mitogen-activated protein kinase 76
protein kinase 69
ERK 44
CD10 34
superoxide dismutase 31
caspase-3 30
proteasome 28
insulin-degrading enzyme 28
beta-secretase 26
acetylcholinesterase 25
GSK 25
ACS 24
protein kinase C 22
AMP-activated protein kinase 21
ATPase 18
AMPK 17
AMPK 17
lactate dehydrogenase 12
choline acetyltransferase 11
catalase 10
more...
Compound
water 283
Dec 178
calcium 102
DNA 90
glucose 76
oxygen 75
TNF 51
iron 43
glutamate 42
ATP 37
FAD 34
APH 32
hydrogen 30
phosphate 26
ACS 24
tyrosine 24
ACS 24
acetate 23
serine 22
Clin 22
more...