Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: HUMANGGP:020876 (PD-1)
 6,353 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
PD-1 6353
PD-L1 2631
CD8 1430
CTLA-4 1276
CD4 962
cytokine 546
IFN 454
Sep 306
Mol 281
PD-L2 269
LAG-3 261
CD28 256
programmed death ligand 1 232
IL-10 230
lymphoid 218
IL-2 217
interferon 197
CTLA4 193
TIM-3 192
BRAF 184
more...
Disease
cancer 3248
tumor 3090
melanoma 867
non-small cell lung cancer 395
tumor growth 394
lung cancer 359
metastatic melanoma 259
metastases 247
HIV 210
breast cancer 200
carcinoma 193
tumor progression 173
adenocarcinoma 172
squamous cell carcinoma 164
colorectal cancer 156
renal cell carcinoma 156
Hodgkin's disease 142
hepatocellular carcinoma 136
lymphoma 114
virus infection 113
more...
Symptom
exhaustion 441
diarrhea 26
fatigue 23
pain 15
weakness 9
splenomegaly 7
dyspnea 7
nausea 6
asthenia 4
starvation 4
myalgia 3
cough 3
respiratory distress 3
collapse 3
analgesia 3
headache 3
anorexia 3
Ill 3
vomiting 3
cachexia 3
more...
Drug
IL-2 218
PDL 88
IFN-gamma 59
Ipilimumab 58
Dermatol 50
CSF 49
lysine 17
Sorafenib 11
ROC 8
ROS 8
ICI 8
Herceptin 6
Provenge 6
Cetuximab 6
CTX 5
ABC 5
Monit 5
Norplant 5
Everolimus 5
CCL 5
more...
Enzyme
ERK 288
granzyme B 114
MEK 98
mitogen-activated protein kinase 75
focal adhesion kinase 71
ACS 30
indoleamine 2,3-dioxygenase 29
PARP 29
APC 24
CD10 22
arginase 20
luciferase 18
protein kinase 15
alanine aminotransferase 15
lactate dehydrogenase 15
proteasome 12
DNA methyltransferase 10
DCF 9
AMP-activated protein kinase 9
IKK 8
more...
Compound
Clin 391
Dec 300
DNA 268
TNF 169
MEK 96
glucose 42
oxygen 41
tyrosine 38
ACS 30
ACS 30
NKT 29
ATP 22
methionine 21
tryptophan 18
phosphate 18
lysine 18
TNM 18
BCG 16
tryptophan 15
tryptophan 15
more...