Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: HUMANGGP:020613 (
Mdm2
)
1,547
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
Mdm2
1547
p53
1383
p21
212
Mol
196
ubiquitin
164
proteasome
125
E3 ubiquitin ligase
111
Sep
91
ubiquitin ligase
88
mdm2
76
ARF
75
Bcl-2
67
MDM2
66
tumour suppressor
65
p53 target
61
ATM
58
mutant p53
46
p300
43
p73
43
Hdm2
42
more...
Disease
cancer
477
tumor
434
tumorigenesis
120
ARF
75
ATM
67
breast cancer
54
carcinogenesis
46
retinoblastoma
35
tumor growth
34
tumor progression
32
MCF
27
prostate cancer
23
colon cancer
22
leukemia
19
lymphoma
19
hepatocellular carcinoma
18
carcinoma
16
melanoma
16
lung cancer
15
neuroblastoma
14
more...
Symptom
collapse
5
acute stress
5
starvation
4
exhaustion
2
hepatomegaly
2
thinning
2
hypothermia
1
hyperoxia
1
ataxia
1
seizures
1
Drug
lysine
31
ROS
14
Adriamycin
7
Parkin
5
Parkin
5
Bortezomib
3
PFT
3
Imatinib
3
IL-2
3
caffeine
2
Dermatol
2
Cardiovasc
2
MDM
2
PTH
1
Simvastatin
1
ABC
1
TAT
1
MAP
1
Gel
1
EE2
1
more...
Enzyme
proteasome
125
mitogen-activated protein kinase
38
caspase-3
27
protein kinase
26
ERK
23
focal adhesion kinase
21
cdc2
20
luciferase
15
PARP
13
phosphatidylinositol 3-kinase
11
MEK
11
caspase-9
11
calcineurin
10
ubiquitin-protein ligase
9
RNA polymerase
8
IKK
8
ATPase
6
glutathione S-transferase
6
protein kinase C
5
caspase-8
5
more...
Compound
DNA
495
Dec
96
urea
76
serine
50
lysine
41
oxygen
28
threonine
20
cysteine
18
alanine
17
tyrosine
16
Clin
15
arginine
15
Ubiquitin
14
zinc
13
Adriamycin
10
hydrogen
10
ATP
10
CHIP
10
MDA
9
calcium
9
more...