Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: HUMANGGP:020180 (
HPRT
)
1,661
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
HPRT
1661
hypoxanthine-guanine phosphoribosyltransferase
253
Mol
172
GAPDH
129
Sep
108
X-linked
94
ACTB
92
B2M
71
housekeeping
70
TBP
64
AMP
60
HAT
60
G6PD
58
SDHA
51
YWHAZ
45
PGK
43
PPIA
42
HMBS
38
IMP
38
p53
37
more...
Disease
cancer
142
Lesch-Nyhan syndrome
125
tumor
74
carcinogenesis
63
lymphoma
40
hyperuricemia
39
gout
35
carcinoma
20
hepatocellular carcinoma
19
leukemia
19
mental retardation
17
mental retardation
17
breast cancer
15
arthritis
15
neuroblastoma
11
lung cancer
11
tumorigenesis
10
choreoathetosis
9
immunodeficiency
9
self-injurious behavior
9
more...
Symptom
dystonia
5
spasticity
5
starvation
5
seizures
4
pain
3
skin irritation
3
hypotonia
2
erythema
2
HSA
2
shortness of breath
1
constipation
1
ataxia
1
Fluctuation
1
dysarthria
1
athetosis
1
nausea
1
cough
1
oliguria
1
anorexia
1
Ill
1
more...
Drug
Mutagen
62
IL-2
11
G418
10
BH4
7
IFN-gamma
6
lysine
6
BLM
4
caffeine
4
vitamin E
4
ACT
3
AGG
3
AZT
3
AZT
3
CSF
3
ascorbate
3
NH3
2
EPA
2
DNase I
2
Lead acetate
2
Adriamycin
2
more...
Enzyme
hypoxanthine-guanine phosphoribosyltransferase
1096
glyceraldehyde-3-phosphate dehydrogenase
133
adenine phosphoribosyltransferase
57
phosphoglycerate kinase
50
thymidine kinase
23
ATPase
18
glucose-6-phosphate dehydrogenase
16
ERK
15
reverse transcriptase
14
adenosine deaminase
13
adenosine deaminase
13
aldehyde dehydrogenase
11
PRPP synthetase
11
5'-nucleotidase
10
glyceraldehyde-3-phosphate dehydrogenase
10
PRT
10
glyceraldehyde-3-phosphate dehydrogenase
10
glyceraldehyde-3-phosphate dehydrogenase
10
superoxide dismutase
10
DNA polymerase
10
more...
Compound
DNA
560
Dec
117
TBP
64
TBP
64
pyrene
57
EMS
40
IMP
38
oxygen
35
sodium
33
Clin
30
pyrimidine
22
pyrimidine
22
acetate
21
methyl methanesulfonate
20
water
19
GMP
18
phosphate
18
MNNG
16
PRPP
14
DMSO
14
more...