Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: HUMANGGP:020180 (HPRT)
1,661 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
HPRT 1661
hypoxanthine-guanine phosphoribosyltransferase 253
Mol 172
GAPDH 129
Sep 108
X-linked 94
ACTB 92
B2M 71
housekeeping 70
TBP 64
AMP 60
HAT 60
G6PD 58
SDHA 51
YWHAZ 45
PGK 43
PPIA 42
HMBS 38
IMP 38
p53 37
more...
Disease
cancer 142
Lesch-Nyhan syndrome 125
tumor 74
carcinogenesis 63
lymphoma 40
hyperuricemia 39
gout 35
carcinoma 20
hepatocellular carcinoma 19
leukemia 19
mental retardation 17
mental retardation 17
breast cancer 15
arthritis 15
neuroblastoma 11
lung cancer 11
tumorigenesis 10
choreoathetosis 9
immunodeficiency 9
self-injurious behavior 9
more...
Symptom
dystonia 5
spasticity 5
starvation 5
seizures 4
pain 3
skin irritation 3
hypotonia 2
erythema 2
HSA 2
shortness of breath 1
constipation 1
ataxia 1
Fluctuation 1
dysarthria 1
athetosis 1
nausea 1
cough 1
oliguria 1
anorexia 1
Ill 1
more...
Drug
Mutagen 62
IL-2 11
G418 10
BH4 7
IFN-gamma 6
lysine 6
BLM 4
caffeine 4
vitamin E 4
ACT 3
AGG 3
AZT 3
AZT 3
CSF 3
ascorbate 3
NH3 2
EPA 2
DNase I 2
Lead acetate 2
Adriamycin 2
more...
Enzyme
hypoxanthine-guanine phosphoribosyltransferase 1096
glyceraldehyde-3-phosphate dehydrogenase 133
adenine phosphoribosyltransferase 57
phosphoglycerate kinase 50
thymidine kinase 23
ATPase 18
glucose-6-phosphate dehydrogenase 16
ERK 15
reverse transcriptase 14
adenosine deaminase 13
adenosine deaminase 13
aldehyde dehydrogenase 11
PRPP synthetase 11
5'-nucleotidase 10
glyceraldehyde-3-phosphate dehydrogenase 10
PRT 10
glyceraldehyde-3-phosphate dehydrogenase 10
glyceraldehyde-3-phosphate dehydrogenase 10
superoxide dismutase 10
DNA polymerase 10
more...
Compound
DNA 560
Dec 117
TBP 64
TBP 64
pyrene 57
EMS 40
IMP 38
oxygen 35
sodium 33
Clin 30
pyrimidine 22
pyrimidine 22
acetate 21
methyl methanesulfonate 20
water 19
GMP 18
phosphate 18
MNNG 16
PRPP 14
DMSO 14
more...