Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: HUMANGGP:019459 (ERK2)
 3,473 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
ERK2 3473
ERK1 1702
ERK 786
MAPK 605
mitogen-activated protein 500
MEK 487
p38 468
extracellular signal-regulated kinase 457
MAP kinase 447
Mol 397
MEK1 367
Sep 246
JNK 239
MAP 190
c-Jun 185
epidermal growth factor 167
protein kinase 2 166
tyrosine kinase 165
threonine 157
phosphatase 157
more...
Disease
cancer 384
tumor 270
breast cancer 97
tumorigenesis 66
pertussis 60
carcinogenesis 57
Alzheimer's disease 54
MCF 53
leukemia 51
carcinoma 50
tumor growth 49
melanoma 46
hepatocellular carcinoma 41
ischemia 39
adenocarcinoma 34
HIV 33
neuroblastoma 33
depression 32
tumor progression 29
lung cancer 28
more...
Symptom
pain 26
starvation 16
seizures 6
analgesia 4
hyperoxia 4
functional recovery 3
despair 2
fatigue 2
memory loss 2
erythema 2
nausea 1
hypercapnia 1
swollen joints 1
diarrhea 1
Neuropathic pain 1
weakness 1
cerebellar ataxia 1
acute stress 1
tremor 1
acute pain 1
more...
Drug
MAP 190
IL-2 27
CSF 24
IFN-gamma 21
ICI 20
ETS 18
lysine 16
ROS 16
Angiotensin II 14
EE2 9
Retinoic acid 7
Estrogens 7
Taxol 6
Asn 6
CAM 6
caffeine 6
p75 5
G-CSF 5
PTH 5
Portal 5
more...
Enzyme
mitogen-activated protein kinase 3123
ERK 930
MEK 797
protein kinase 524
protein kinase C 298
MAP 190
focal adhesion kinase 160
phosphatidylinositol 3-kinase 98
luciferase 83
calcineurin 63
MEKK1 59
phospholipase C 58
caspase-3 46
thrombin 37
AMPK 33
glutathione S-transferase 32
catalase 26
phosphoinositide 3-kinase 26
CaMKII 24
NADPH oxidase 21
more...
Compound
tyrosine 455
MEK 421
DNA 317
Dec 243
threonine 234
calcium 208
serine 203
MAP 190
acetate 134
cAMP 131
ATP 121
oxygen 103
glucose 63
alanine 56
sodium 54
phosphate 53
NH2 52
TNF 51
glutamate 48
hydrogen 46
more...