Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: HUMANGGP:018856 (
AP-1
)
11,304
document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
AP-1
11304
c-Jun
2252
Mol
1427
JNK
1027
cytokine
944
p38
932
c-fos
928
Sep
795
MAPK
762
ERK
642
ERK1
496
IL-6
495
TNF
434
AP-2
421
lipopolysaccharide
420
CREB
406
p65
398
tumor necrosis factor
386
IL-8
339
mitogen-activated protein
336
more...
Disease
cancer
1287
tumor
1053
carcinogenesis
302
breast cancer
290
tumorigenesis
261
hepatocellular carcinoma
209
carcinoma
203
leukemia
182
HIV
173
atherosclerosis
169
tumor progression
136
diabetes
133
tumor growth
129
MCF
125
immunodeficiency
117
melanoma
116
ischemia
106
Epstein
104
rheumatoid arthritis
104
asthma
104
more...
Symptom
seizures
51
starvation
28
pain
26
skin damage
19
hyperoxia
14
diarrhea
11
cachexia
10
respiratory distress
9
exhaustion
8
functional recovery
7
erythema
7
collapse
6
cough
4
hypothermia
4
headache
4
fatigue
3
hepatomegaly
3
HSA
3
thinning
3
anesthesia
3
more...
Drug
IL-2
268
Gel
199
DNase I
133
ROS
120
IFN-gamma
116
MAP
112
Dermatol
81
lysine
61
CSF
60
ETS
47
ICI
30
Heme
29
Retinoic acid
29
Angiotensin II
24
vitamin E
20
Arsenic trioxide
19
IL-11
19
Glutathione
18
uPA
18
Cardiovasc
17
more...
Enzyme
mitogen-activated protein kinase
2488
ERK
826
luciferase
719
protein kinase C
633
protein kinase
553
MEK
435
collagenase
324
catalase
210
chloramphenicol acetyltransferase
169
focal adhesion kinase
155
IKK
145
calcineurin
119
MAP
112
MMP-3
112
glutathione S-transferase
100
caspase-3
98
proteasome
93
MEKK1
92
phosphatidylinositol 3-kinase
91
NADPH oxidase
90
more...
Compound
DNA
3071
Dec
851
acetate
663
oxygen
613
TNF
434
calcium
414
cAMP
387
tyrosine
322
ATF
249
nitric oxide
243
MEK
215
retinoic acid
194
PMA
192
PMA
191
cysteine
182
TPA
171
TPA
171
AMP
164
serine
164
THP
160
more...