Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: HUMANGGP:017274 (
P-glycoprotein
)
13,241
document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
P-glycoprotein
13241
MDR1
1886
ATP
1289
ABCB1
1040
Sep
912
P-gp
778
Mol
760
breast cancer resistance protein
713
ATP-binding cassette
709
ATPase
687
cytochrome P450
646
mdr1
493
multidrug resistance-associated protein
492
CYP3A4
462
MRP1
436
ADR
390
ABC
357
ABCG2
356
BCRP
344
ABCC1
333
more...
Disease
cancer
3936
tumor
2053
leukemia
695
breast cancer
671
MCF
530
carcinoma
395
acute myeloid leukemia
301
lymphoma
220
epilepsy
215
hepatocellular carcinoma
214
adenocarcinoma
209
CEM
204
HIV
199
lung cancer
176
tumor growth
174
Alzheimer's disease
144
ovarian cancer
134
Leukemia
131
GSH
121
multiple myeloma
120
more...
Symptom
seizures
113
pain
50
diarrhea
44
analgesia
31
nausea
25
starvation
21
vomiting
18
constipation
15
anesthesia
12
headache
11
ataxia
9
dizziness
8
angina
8
sleepiness
7
fatigue
7
nausea and vomiting
7
hypothermia
6
insomnia
4
tremor
4
acidity
4
more...
Drug
ADR
390
ABC
357
Adriamycin
195
Taxol
117
ADM
113
VCR
99
VCR
91
Cremophor EL
40
CPT-11
38
Tacrolimus
38
Monit
37
CSF
34
Docetaxel
32
ROS
32
IL-2
29
Imatinib
28
lysine
28
Etoposide
27
caffeine
23
Tariquidar
23
more...
Enzyme
P-glycoprotein
13241
ATPase
703
MDR
585
CYP3A4
462
topoisomerase
265
topoisomerase
244
protein kinase C
173
glutathione S-transferase
164
ERK
157
mitogen-activated protein kinase
153
reverse transcriptase
127
caspase-3
121
protein kinase
96
ACS
66
catalase
56
luciferase
54
PARP
51
glutathione peroxidase
46
calcineurin
44
RNA polymerase
42
more...
Compound
ATP
1289
Dec
931
DNA
752
Clin
635
MDR
585
ADR
511
Adriamycin
328
MTT
328
sodium
283
Verapamil
268
Verapamil
267
water
256
PEG
207
oxygen
205
calcium
192
Cyclosporine
156
GSH
137
GSH
137
VP-16
131
Rhodamine 123
131
more...