Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: HUMANGGP:015780 (poly(ADP-ribose) polymerase)
 4,694 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
poly(ADP-ribose) polymerase 4694
PARP 1899
caspase-3 1285
PARP-1 649
Bcl-2 562
Mol 512
ADP 509
cytochrome c 482
p53 401
NAD 369
caspase-9 356
Sep 347
caspase-8 295
PARP1 247
ATP 237
Fas 180
NAD+ 173
BRCA1 170
annexin V 140
p21 139
more...
Disease
cancer 1323
tumor 601
breast cancer 275
leukemia 218
carcinoma 144
ovarian cancer 139
ischemia 136
MCF 113
diabetes 110
prostate cancer 107
tumor growth 105
carcinogenesis 99
colon cancer 93
hepatocellular carcinoma 89
melanoma 73
tumorigenesis 64
lung cancer 64
ATM 59
retinoblastoma 55
stroke 55
more...
Symptom
collapse 25
starvation 14
diarrhea 11
nausea 10
pain 9
seizures 8
fatigue 8
vomiting 8
erythema 7
functional recovery 6
hyperoxia 5
respiratory distress 5
skin damage 5
anesthesia 5
asthenia 4
ataxia 3
decreased appetite 3
hypothermia 3
nausea and vomiting 2
stigma 2
more...
Drug
ROS 44
lysine 37
caffeine 23
NADH 21
CED 20
niacin 16
Dermatol 15
DNase I 12
ascorbate 12
Mutagen 11
Taxol 10
vitamin E 10
Cardiovasc 10
IL-2 9
IFN-gamma 9
AMC 8
CPT-11 7
MAP 7
Gel 7
Arsenic trioxide 7
more...
Enzyme
PARP 2366
caspase-3 1130
mitogen-activated protein kinase 331
caspase-9 308
caspase-8 244
protein kinase 164
ERK 122
poly(ADP-ribose) glycohydrolase 94
caspase-1 93
topoisomerase 70
DNA ligase 69
DNA ligase 69
caspase-7 68
protein kinase C 66
topoisomerase 66
superoxide dismutase 65
catalase 64
proteasome 64
caspase-7 63
phosphatidylinositol 3-kinase 61
more...
Compound
DNA 2239
NAD 525
ADP 519
ADP 510
ADP 509
oxygen 503
ADP-ribose 445
NAD 369
Dec 336
3-aminobenzamide 245
ATP 237
nicotinamide 206
Asp 133
Clin 129
nitric oxide 128
cysteine 117
PAR 115
calcium 108
glucose 106
hydrogen 105
more...