Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: HUMANGGP:015022 (
p27
)
7,799
document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
p27
7799
p21
2916
p53
1309
cyclin D1
1252
cyclin-dependent kinase
975
cyclin E
928
cyclin
888
Mol
865
p16
568
Sep
515
CDK2
498
caspase-3
480
cyclin A
472
Bcl-2
466
CDK4
432
Skp2
377
cyclin-dependent kinase inhibitor
333
proteasome
295
ubiquitin
290
AKT
283
more...
Disease
cancer
2376
tumor
2028
breast cancer
574
retinoblastoma
504
tumorigenesis
498
carcinoma
408
tumor growth
358
carcinogenesis
327
prostate cancer
301
leukemia
292
hepatocellular carcinoma
233
tumor progression
194
MCF
193
lung cancer
167
squamous cell carcinoma
160
adenocarcinoma
152
immunodeficiency
149
melanoma
144
colon cancer
142
lymphoma
132
more...
Symptom
starvation
65
diarrhea
10
collapse
10
functional recovery
10
seizures
9
splenomegaly
9
exhaustion
7
hypothermia
3
cachexia
3
pain
3
paresis
2
hepatomegaly
2
anesthesia
2
anorexia
2
hyperoxia
2
dyspnea
2
abdominal pain
2
intestinal bleeding
1
angina
1
vomiting
1
more...
Drug
ROS
56
IL-2
47
MAP
38
lysine
28
Herceptin
24
IFN-gamma
18
Dermatol
17
Bortezomib
16
ICI
15
Lovastatin
15
Gefitinib
13
Retinoic acid
12
vitamin E
12
Cardiovasc
12
Monit
12
Imatinib
11
Simvastatin
9
CAM
9
Angiotensin II
8
TAT
8
more...
Enzyme
protein kinase
1173
cdc2
998
mitogen-activated protein kinase
618
ERK
451
caspase-3
376
proteasome
297
PARP
191
focal adhesion kinase
144
MEK
137
caspase-9
126
luciferase
118
phosphatidylinositol 3-kinase
104
protein kinase C
72
reverse transcriptase
67
caspase-8
64
AMP-activated protein kinase
54
GSK
54
phosphoinositide 3-kinase
53
AMPK
38
APC
37
more...
Compound
DNA
1007
Dec
543
oxygen
231
MTT
186
threonine
181
Clin
163
MDA
140
tyrosine
131
glucose
117
serine
104
MEK
98
retinoic acid
89
cAMP
77
calcium
67
sodium
63
ATP
60
acetate
55
TNF
52
vitamin D
52
phosphate
51
more...