Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: HUMANGGP:015000 (
histone H3
)
10,526
document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
histone H3
10526
histone
4430
Mol
1529
histone deacetylase
863
methyltransferase
818
Sep
600
telomeric
595
histone H4
550
histone methyltransferase
488
RNA polymerase II
426
p53
331
histone acetyltransferase
316
CENP-A
306
SET
303
EZH2
271
H2A
263
H2B
252
p300
245
HDAC1
215
p21
202
more...
Disease
cancer
1528
tumor
968
tumorigenesis
320
leukemia
301
breast cancer
262
carcinogenesis
192
prostate cancer
150
HP1
150
tumor growth
146
carcinoma
123
hepatocellular carcinoma
123
acute myeloid leukemia
119
tumor progression
108
glioma
100
lung cancer
89
retinoblastoma
76
diabetes
71
lymphoma
70
MCF
69
adenocarcinoma
68
more...
Symptom
pain
32
starvation
28
seizures
14
ataxia
9
fatigue
8
hypotonia
6
diarrhea
5
functional recovery
5
acute stress
5
nausea
4
anorexia
4
dystonia
4
respiratory distress
4
neurological disability
3
vomiting
3
CSR
3
splenomegaly
2
analgesia
2
collapse
2
thinning
2
more...
Drug
lysine
4327
DNase I
65
ROS
20
IL-2
16
Vorinostat
15
FAD
14
Dermatol
14
Gel
13
Ethanol
11
Mutagen
11
Leaf
11
MAP
11
IFN-gamma
11
p75
10
NADH
9
caffeine
9
ETS
9
MOF
8
ascorbate
8
Arsenic trioxide
8
more...
Enzyme
RNA polymerase
492
demethylase
430
histone acetyltransferase
333
mitogen-activated protein kinase
302
protein kinase
228
histone demethylase
201
ERK
191
Lys4
158
DNA methyltransferase
155
caspase-3
105
luciferase
85
ATPase
77
proteasome
73
PHD
71
focal adhesion kinase
67
PARP
59
cdc2
57
ACS
53
MEK
47
topoisomerase
47
more...
Compound
lysine
4750
DNA
3230
Dec
761
Histone
560
serine
383
SET
303
arginine
247
threonine
180
sodium
161
oxygen
154
ATP
137
glucose
133
methionine
109
Clin
92
water
85
cAMP
83
tyrosine
79
barium
78
acetate
77
retinoic acid
76
more...