Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: HUMANGGP:014525 (phosphodiesterase)
 17,939 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
phosphodiesterase 17939
AMP 2672
adenylate cyclase 1645
Sep 1246
calmodulin 1026
Mol 1017
PDE 851
ATP 697
PDE4 646
insulin 607
adenylyl cyclase 580
guanylate cyclase 564
cyclic nucleotide phosphodiesterase 561
GTP 396
GMP 394
cyclic AMP phosphodiesterase 379
PDE5 374
nitric oxide synthase 353
cAMP-dependent protein kinase 334
ADP 320
more...
Disease
erectile dysfunction 1006
PDE 851
hypertension 594
heart failure 508
pulmonary hypertension 473
cancer 449
asthma 438
diabetes 356
chronic obstructive pulmonary disease 339
tumor 327
cholera 290
stroke 233
depression 233
pertussis 232
ischemia 231
congestive heart failure 190
NAME 150
atopic dermatitis 132
atherosclerosis 131
Pulmonary arterial hypertension 128
more...
Symptom
headache 130
pain 120
vomiting 76
anesthesia 71
starvation 71
nausea 70
diarrhea 68
dyspnea 52
flushing 51
seizures 47
fatigue 39
angina 28
hypothermia 27
ataxia 25
functional recovery 23
hyperoxia 22
cough 22
respiratory distress 21
nasal congestion 20
spasm 20
more...
Drug
caffeine 374
Rolipram 301
Cardiovasc 296
Forskolin 240
Theophylline 181
Cilostazol 168
Viagra 166
CIA 156
Dermatol 150
Viagra 118
Vardenafil 94
Roflumilast 78
Roflumilast 78
ICI 68
Enoximone 68
Papaverine 67
Amrinone 63
nitroglycerin 62
Histamine 55
Nephron 52
more...
Enzyme
phosphodiesterase 17939
adenylate cyclase 1777
protein kinase 1750
PDE 1492
guanylate cyclase 772
cGMP phosphodiesterase 409
protein kinase C 382
AMPK 346
alkaline phosphatase 292
ATPase 274
PKG 231
mitogen-activated protein kinase 223
NO synthase 202
phospholipase C 174
nucleotide pyrophosphatase 163
calcineurin 155
thrombin 144
5'-nucleotidase 140
acid phosphatase 138
trypsin 126
more...
Compound
cAMP 4807
cGMP 2835
AMP 2834
calcium 2510
Dec 1262
nitric oxide 1176
GMP 960
sodium 913
ATP 698
phosphate 690
Clin 653
DNA 652
oxygen 567
glucose 480
Sildenafil 457
arginine 452
prostacyclin 402
GTP 396
ADP 375
caffeine 374
more...