Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: HUMANGGP:014504 (
Proteasome
)
1,413
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
Proteasome
1413
proteasome
1033
ubiquitin
391
proteasome inhibitor
280
Mol
143
Ubiquitin
134
Sep
83
p53
78
chymotrypsin-like
68
endoplasmic reticulum
67
ATP
49
ATPase
39
p21
36
caspase-3
35
Bcl-2
33
peptidase
30
cytokine
27
p27
25
MHC class I
23
caspase-8
21
more...
Disease
cancer
343
multiple myeloma
226
tumor
159
leukemia
38
tumor growth
36
Alzheimer's disease
33
breast cancer
30
mantle cell lymphoma
29
hematologic malignancies
28
prostate cancer
25
Parkinson's disease
25
HIV
21
peripheral neuropathy
21
lymphoma
19
carcinoma
18
diabetes
17
neuroblastoma
16
hepatocellular carcinoma
15
Leukemia
15
colon cancer
15
more...
Symptom
starvation
8
pain
7
fatigue
6
diarrhea
5
nausea
4
vomiting
3
collapse
3
cachexia
3
arthralgia
2
respiratory distress
2
hyperoxia
2
weakness
2
myalgia
2
insomnia
2
headache
1
exhaustion
1
numbness
1
asthenia
1
functional recovery
1
Diaphragmatic weakness
1
more...
Drug
Bortezomib
108
lysine
21
AMC
12
Parkin
8
Parkin
8
ROS
7
IFN-gamma
6
Cardiovasc
6
Dermatol
4
Gel
3
Ethanol
3
Irinotecan
2
Amiloride
2
IL-2
2
Adriamycin
2
ADM
2
Gleevec
2
2-Methoxyestradiol
2
Gefitinib
2
Imatinib
2
more...
Enzyme
proteasome
1039
mitogen-activated protein kinase
56
protein kinase
46
ATPase
40
trypsin
40
caspase-3
26
caspase-8
18
ERK
16
chymotrypsin
15
focal adhesion kinase
13
luciferase
13
caspase-9
12
cathepsin B
11
MEK
10
AMPK
9
protein kinase C
9
calcineurin
8
PARP
8
IKK
7
reverse transcriptase
7
more...
Compound
Ubiquitin
124
DNA
121
Dec
99
ATP
49
oxygen
41
Clin
31
leucine
26
tyrosine
26
lysine
24
Cardiol
18
calcium
15
glucose
15
alanine
14
cysteine
12
serine
12
threonine
11
aldehyde
10
arginine
10
nitric oxide
10
TNF
10
more...