Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: HUMANGGP:014371 (
CD28
)
8,421
document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
CD28
8421
CD4
2237
cytokine
1659
IL-2
1564
CD8
1543
TCR
1171
CD80
902
CTLA-4
896
IL-4
815
IFN-gamma
806
CD25
752
CD86
717
T cell receptor
629
IL-10
621
Sep
542
IFN
456
CD2
452
CD40
451
CTLA4
414
B7-2
412
more...
Disease
tumor
927
cancer
877
HIV
429
immunodeficiency
246
rheumatoid arthritis
230
APC
221
autoimmune disease
220
leukemia
188
cytomegalovirus
183
graft-versus-host disease
155
melanoma
148
lymphoma
144
multiple sclerosis
137
systemic lupus erythematosus
133
diabetes
117
encephalomyelitis
117
AIDS
113
PHA
109
Blocking
108
infectious diseases
105
more...
Symptom
exhaustion
98
splenomegaly
16
pain
10
HSA
8
dyspnea
8
starvation
7
diarrhea
7
respiratory distress
5
erythema
5
nausea
5
fatigue
5
weakness
5
headache
4
collapse
3
chills
3
hepatosplenomegaly
3
memory loss
3
cough
2
overweight
2
hypothermia
2
more...
Drug
IL-2
1568
IFN-gamma
797
CSF
96
Dermatol
49
Belatacept
37
Abatacept
36
MAP
17
p75
17
Asthma
15
lysine
13
G-CSF
11
PDL
10
IFN-beta
8
Campath
6
Allergen
6
Ipilimumab
6
CAM
6
Campath
6
Infliximab
6
Infliximab
6
more...
Enzyme
mitogen-activated protein kinase
232
APC
221
protein kinase C
174
ERK
130
granzyme B
116
protein kinase
112
focal adhesion kinase
105
phosphatidylinositol 3-kinase
91
calcineurin
80
IKK
40
MEK
40
luciferase
36
reverse transcriptase
34
phosphoinositide 3-kinase
29
phospholipase C
28
caspase-3
25
proteasome
22
indoleamine 2,3-dioxygenase
22
CD10
18
arginase
16
more...
Compound
Dec
618
Clin
572
DNA
342
calcium
283
tyrosine
283
TNF
261
acetate
242
PMA
215
PMA
212
cAMP
68
oxygen
66
Optimal
51
glucose
50
serine
43
Cbl
40
NKT
38
FK506
32
tryptophan
32
threonine
31
ATP
30
more...