Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: HUMANGGP:014333 (
HDAC
)
2,437
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
HDAC
2437
histone
655
histone deacetylase
487
HDAC1
298
Mol
253
Sep
154
histone H3
140
HDAC2
139
HDAC6
124
p53
118
p21
110
Histone deacetylase
110
HDAC3
102
histone deacetylase 1
85
TSA
73
DNMT1
68
mTOR
67
HAT
64
HDAC4
63
p300
63
more...
Disease
cancer
775
tumor
461
breast cancer
123
leukemia
93
tumor growth
87
acute myeloid leukemia
80
tumorigenesis
68
MCF
51
carcinoma
50
prostate cancer
48
lymphoma
44
multiple myeloma
43
lung cancer
42
tumor progression
42
hepatocellular carcinoma
42
colon cancer
38
non-small cell lung cancer
30
Alzheimer's disease
28
melanoma
28
carcinogenesis
27
more...
Symptom
pain
9
fatigue
9
starvation
7
seizures
6
nausea
4
ataxia
4
functional recovery
4
anorexia
3
weakness
3
splenomegaly
3
vomiting
2
erythema
2
memory loss
2
diarrhea
2
Halo
1
Neuropathic pain
1
tinnitus
1
dizziness
1
tremor
1
disturbed balance
1
more...
Drug
lysine
138
Vorinostat
47
ROS
21
Romidepsin
20
NVP
5
NADH
5
IL-2
5
MDS
4
Herceptin
3
Retinoic acid
3
Mutagen
3
DNase I
3
Imatinib
3
G-CSF
3
Bortezomib
3
ETS
3
Cardiovasc
3
Gel
3
ENT
2
Glutathione
2
more...
Enzyme
ERK
121
mitogen-activated protein kinase
83
TSA
74
histone acetyltransferase
61
protein kinase
53
proteasome
52
focal adhesion kinase
40
luciferase
39
PARP
36
MEK
36
DNA methyltransferase
33
ACS
29
caspase-3
28
cdc2
26
RNA polymerase
20
protein kinase C
18
AMPK
18
AMP-activated protein kinase
17
glutathione S-transferase
16
AMPK
16
more...
Compound
DNA
419
lysine
154
Dec
145
sodium
101
Histone
88
zinc
75
MDA
59
oxygen
54
Valproic acid
40
Clin
38
TNF
36
MEK
35
calcium
34
serine
30
ACS
29
ACS
29
glucose
28
MTT
27
water
24
Valproic acid
23
more...