Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: HUMANGGP:013463 (PKB)
 2,642 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
PKB 2642
protein kinase B 813
insulin 618
AKT 435
PI3K 361
Mol 293
phosphatidylinositol 3-kinase 259
mTOR 239
MAPK 208
ERK1 177
ERK 172
Sep 171
phosphoinositide 3-kinase 164
PTEN 157
IRS-1 148
p38 133
PKC 127
phosphatase 123
insulin receptor 119
GSK 114
more...
Disease
cancer 429
tumor 304
diabetes 138
type 2 diabetes 86
obesity 82
breast cancer 76
tumorigenesis 67
hepatocellular carcinoma 55
tumor growth 43
tumor progression 43
ischemia 39
prostate cancer 38
Alzheimer's disease 36
hyperglycemia 31
carcinoma 29
carcinogenesis 29
leukemia 26
neuroblastoma 26
hyperinsulinemia 24
glioma 24
more...
Symptom
starvation 28
pain 11
functional recovery 10
seizures 4
collapse 3
overweight 2
dry eye 2
thinning 2
weakness 1
acute pain 1
splenomegaly 1
Noise-induced hearing loss 1
hyperoxia 1
ataxia 1
apathy 1
CSR 1
nausea 1
angina 1
Scratch 1
vomiting 1
more...
Drug
MAP 33
ROS 26
lysine 11
CSF 10
Angiotensin II 7
ICI 7
Glucagon 6
Herceptin 5
Simvastatin 5
Dermatol 5
EE2 5
IFN-gamma 5
Cardiovasc 5
ascorbate 5
vitamin E 4
IL-2 4
IL-1ra 3
Heme 3
Ethanol 3
Gefitinib 3
more...
Enzyme
focal adhesion kinase 2642
mitogen-activated protein kinase 549
protein kinase 509
phosphatidylinositol 3-kinase 261
ERK 241
protein kinase C 210
phosphoinositide 3-kinase 164
GSK 124
MEK 116
PDK1 105
AMP-activated protein kinase 93
caspase-3 81
AMPK 58
AMPK 47
calcineurin 32
MAP 32
proteasome 25
PARP 22
luciferase 20
phospholipase C 20
more...
Compound
glucose 369
Dec 207
tyrosine 204
DNA 189
threonine 182
serine 177
Insulin 164
oxygen 106
cAMP 100
MEK 81
calcium 80
ATP 68
nitric oxide 58
phosphate 53
Clin 43
Wortmannin 41
Phosphatidylinositol 41
alanine 37
sodium 37
TNF 36
more...