Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: HUMANGGP:012984 (proton pump)
7,790 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
proton pump 7790
ATPase 970
Sep 517
ATP 414
gastrin 254
CYP2C19 183
Mol 157
cytochrome P450 157
rhodopsin 128
cytochrome c oxidase 102
COX-2 93
gut 88
all-trans 72
membrane protein 68
membrane-bound 65
cytochrome 63
somatostatin 63
cyclooxygenase-2 60
She 57
polypeptide 57
more...
Disease
gastroesophageal reflux disease 1497
peptic ulcer 595
esophagitis 517
cancer 415
Barrett's esophagus 305
Helicobacter pylori infection 292
dyspepsia 286
gastritis 267
dysphagia 245
tumor 232
gastric cancer 222
adenocarcinoma 217
Esophageal 180
duodenal ulcer 173
gastric ulcer 159
reflux esophagitis 149
atrophic gastritis 119
dysplasia 114
asthma 112
Eosinophilic esophagitis 110
more...
Symptom
heartburn 357
acidity 186
pain 183
diarrhea 160
regurgitation 125
chest pain 117
vomiting 93
abdominal pain 84
epigastric pain 71
nausea 67
cough 64
chronic cough 57
hoarseness 42
acid regurgitation 42
anesthesia 32
constipation 29
bloating 27
discomfort 26
discomfort 26
headache 25
more...
Drug
Omeprazole 277
NADH 48
Clopidogrel 45
Cardiovasc 45
Histamine 38
Misoprostol 29
lysine 29
Asn 21
ascorbate 19
Asthma 18
Dermatol 15
AMC 14
Ranitidine 14
Indomethacin 13
ENT 12
caffeine 10
Pantoprazole sodium 9
Sucralfate 9
Cimetidine 9
ampicillin 9
more...
Enzyme
ATPase 1007
urease 87
urease 87
pepsin 73
CYP3A4 55
ATP synthase 43
complex I 42
cytochrome oxidase 40
protein kinase 37
mitogen-activated protein kinase 32
carbonic anhydrase 29
ERK 25
transhydrogenase 23
H,K-ATPase 22
ACS 22
P-glycoprotein 21
peroxidase 19
trypsin 18
proton-translocating ATPase 16
superoxide dismutase 15
more...
Compound
Clin 750
Dec 539
ATP 414
water 321
sodium 298
Omeprazole 287
hydrogen 265
calcium 248
potassium 191
oxygen 146
urea 112
DNA 111
salt 98
Lansoprazole 96
PPI 96
glucose 94
iron 92
phosphate 83
Pantoprazole 71
Asp 68
more...