Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: HUMANGGP:012540 (
ERK1
)
22,678
document(s) hit in 31,850,051 MEDLINE articles (0.04 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
ERK1
22678
p38
4718
MAPK
3993
ERK
3657
Mol
2763
JNK
2380
MEK
2032
extracellular signal-regulated kinase
1929
ERK2
1702
AKT
1697
MEK1
1658
mitogen-activated protein
1536
Sep
1432
extracellular signal-regulated kinase 1
1421
cytokine
1289
PI3K
1283
caspase-3
1103
MAP kinase
927
TNF
911
c-Jun
858
more...
Disease
cancer
3183
tumor
2388
breast cancer
834
tumor growth
572
ischemia
529
tumorigenesis
459
diabetes
433
atherosclerosis
400
hepatocellular carcinoma
379
carcinoma
361
tumor progression
358
MCF
357
carcinogenesis
339
lung cancer
326
melanoma
322
Alzheimer's disease
298
pertussis
296
hypertension
288
prostate cancer
286
adenocarcinoma
280
more...
Symptom
pain
222
starvation
82
seizures
58
functional recovery
45
diarrhea
34
collapse
33
hyperoxia
27
anesthesia
24
analgesia
23
hypothermia
17
respiratory distress
15
fatigue
15
headache
11
Neuropathic pain
11
weakness
11
memory loss
10
vomiting
10
pelvic pain
8
overweight
8
acute stress
8
more...
Drug
MAP
616
ROS
329
IL-2
118
Angiotensin II
111
CSF
102
IFN-gamma
92
ICI
91
lysine
80
Dermatol
77
Cardiovasc
58
Gefitinib
40
uPA
40
Monit
38
vitamin E
37
Sorafenib
31
EE2
31
Gelatin
31
ETS
30
Ouabain
28
Simvastatin
27
more...
Enzyme
mitogen-activated protein kinase
22200
ERK
4665
MEK
3500
protein kinase
2317
protein kinase C
1495
focal adhesion kinase
1007
caspase-3
850
MAP
603
phosphatidylinositol 3-kinase
568
luciferase
415
NADPH oxidase
356
NADPH oxidase
299
PARP
282
phospholipase C
277
superoxide dismutase
269
AMP-activated protein kinase
238
GSK
210
phosphoinositide 3-kinase
207
calcineurin
206
catalase
195
more...
Compound
MEK
1933
Dec
1597
oxygen
1593
DNA
1587
tyrosine
1270
calcium
1148
TNF
911
cAMP
806
glucose
784
MAP
600
serine
584
nitric oxide
582
threonine
495
MTT
447
acetate
415
ATP
373
sodium
357
Clin
349
phosphate
336
water
330
more...