Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: HUMANGGP:011718 (
MAPK
)
31,437
document(s) hit in 31,850,051 MEDLINE articles (0.03 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
MAPK
31437
p38
11054
ERK
5915
JNK
4654
ERK1
3993
PI3K
3370
Mol
3218
MEK
2466
cytokine
2173
AKT
2051
Sep
1953
TNF
1845
IL-6
1546
caspase-3
1291
mTOR
1215
p53
1180
insulin
1101
c-Jun
1019
BRAF
957
MEK1
936
more...
Disease
cancer
5287
tumor
3696
breast cancer
1182
tumorigenesis
855
melanoma
842
tumor growth
775
carcinoma
566
hepatocellular carcinoma
505
tumor progression
501
diabetes
491
carcinogenesis
489
MCF
454
ischemia
442
lung cancer
430
Alzheimer's disease
430
colorectal cancer
424
leukemia
423
atherosclerosis
394
obesity
388
adenocarcinoma
355
more...
Symptom
pain
258
starvation
130
seizures
58
functional recovery
50
diarrhea
48
analgesia
29
collapse
29
respiratory distress
25
skin damage
23
fatigue
23
exhaustion
21
anesthesia
20
cachexia
17
hyperoxia
17
hypothermia
16
splenomegaly
15
Neuropathic pain
13
Scratch
13
headache
12
acute stress
12
more...
Drug
ROS
679
MAP
447
IL-2
189
IFN-gamma
165
Dermatol
146
CSF
138
lysine
114
ICI
79
Angiotensin II
76
ETS
64
Cardiovasc
52
Monit
52
ascorbate
48
Sorafenib
40
Gefitinib
40
Ethanol
39
p75
39
GEO
35
Heme
34
Cetuximab
31
more...
Enzyme
mitogen-activated protein kinase
30542
ERK
7296
MEK
3532
protein kinase
2416
protein kinase C
1484
focal adhesion kinase
1038
caspase-3
1016
luciferase
544
phosphatidylinositol 3-kinase
538
MEKK1
423
AMP-activated protein kinase
412
MAP
410
superoxide dismutase
396
NADPH oxidase
378
PARP
363
NADPH oxidase
343
AMPK
327
calcineurin
309
AMPK
290
catalase
284
more...
Compound
DNA
2367
MEK
2237
Dec
2164
oxygen
2030
TNF
1845
tyrosine
1428
calcium
1222
glucose
965
cAMP
807
serine
741
nitric oxide
712
threonine
677
Clin
572
ATP
455
MTT
450
MAP
414
MDA
405
sodium
400
water
361
acetate
359
more...