Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: HUMANGGP:011717 (
JNK
)
16,370
document(s) hit in 31,850,051 MEDLINE articles (0.03 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
JNK
16370
p38
6936
MAPK
4654
ERK
4320
ERK1
2380
c-Jun
2153
Mol
1616
TNF
1469
caspase-3
1447
cytokine
1331
mitogen-activated protein
1174
IL-6
1109
Bcl-2
1046
Sep
1031
AP-1
1027
PI3K
834
lipopolysaccharide
803
p53
800
tumor necrosis factor
750
AKT
730
more...
Disease
cancer
2424
tumor
1571
breast cancer
436
diabetes
390
hepatocellular carcinoma
373
ischemia
365
Alzheimer's disease
362
tumorigenesis
350
tumor growth
336
obesity
314
GSH
310
atherosclerosis
285
carcinoma
271
leukemia
236
lung cancer
219
carcinogenesis
218
tumor progression
191
MCF
185
prostate cancer
177
Parkinson's disease
175
more...
Symptom
pain
110
starvation
63
collapse
31
seizures
26
functional recovery
23
diarrhea
21
respiratory distress
19
hypothermia
18
fatigue
16
hyperoxia
14
skin damage
13
anesthesia
12
memory loss
12
analgesia
11
overweight
9
cachexia
8
Neuropathic pain
8
splenomegaly
7
low back pain
6
HSA
6
more...
Drug
ROS
616
MAP
579
IL-2
118
IFN-gamma
90
CSF
66
lysine
65
Dermatol
58
p75
52
Angiotensin II
43
Arsenic trioxide
37
vitamin E
36
Monit
35
Heme
30
Cardiovasc
30
ICI
29
ascorbate
28
Ethanol
25
IFN-beta
23
TAK
22
uPA
20
more...
Enzyme
mitogen-activated protein kinase
16370
ERK
4570
MEK
1385
caspase-3
1138
protein kinase
990
protein kinase C
650
MAP
570
focal adhesion kinase
470
PARP
443
superoxide dismutase
338
MEKK1
335
luciferase
327
IKK
289
caspase-9
286
catalase
259
AMP-activated protein kinase
256
caspase-8
248
NADPH oxidase
200
phosphatidylinositol 3-kinase
200
proteasome
183
more...
Compound
oxygen
1683
TNF
1469
DNA
1445
Dec
1177
MEK
652
glucose
627
MAP
571
tyrosine
536
nitric oxide
528
calcium
515
serine
373
MTT
338
GSH
319
GSH
319
cysteine
298
N-acetylcysteine
297
threonine
293
water
262
acetate
244
MDA
236
more...