Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: HUMANGGP:011716 (
ERK
)
26,251
document(s) hit in 31,850,051 MEDLINE articles (0.03 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
ERK
26251
MAPK
5915
MEK
5327
p38
5000
JNK
4320
ERK1
3657
AKT
2995
Mol
2711
PI3K
2571
Sep
1686
cytokine
1387
mTOR
1170
caspase-3
1138
MEK1
1109
MAP kinase
1098
TNF
1095
mitogen-activated protein
1085
extracellular signal-regulated kinase
1002
IL-6
992
Bcl-2
939
more...
Disease
cancer
5186
tumor
3745
breast cancer
1038
tumor growth
912
tumorigenesis
838
melanoma
755
hepatocellular carcinoma
641
tumor progression
595
lung cancer
539
carcinoma
519
leukemia
425
carcinogenesis
417
adenocarcinoma
414
colorectal cancer
412
ischemia
397
MCF
387
diabetes
349
Alzheimer's disease
345
non-small cell lung cancer
326
colon cancer
308
more...
Symptom
pain
274
starvation
92
seizures
55
functional recovery
36
collapse
30
diarrhea
28
analgesia
28
hypothermia
20
respiratory distress
20
memory loss
19
hyperoxia
17
fatigue
15
skin damage
14
anesthesia
14
headache
12
exhaustion
11
splenomegaly
10
Neuropathic pain
10
nausea
9
weakness
9
more...
Drug
MAP
680
ROS
495
IL-2
172
CSF
107
Dermatol
104
Sorafenib
102
lysine
102
IFN-gamma
99
ICI
72
Angiotensin II
60
Monit
57
ETS
55
uPA
44
Cardiovasc
42
Gefitinib
40
NVP
31
caffeine
30
Heme
29
Arsenic trioxide
28
p75
28
more...
Enzyme
ERK
26251
mitogen-activated protein kinase
13210
MEK
6082
protein kinase
2153
protein kinase C
1359
focal adhesion kinase
1178
caspase-3
885
MAP
671
phosphatidylinositol 3-kinase
533
luciferase
500
PARP
363
AMP-activated protein kinase
284
superoxide dismutase
263
calcineurin
247
AMPK
232
proteasome
221
GSK
214
phosphoinositide 3-kinase
210
caspase-9
210
catalase
210
more...
Compound
MEK
5240
Dec
1768
DNA
1763
oxygen
1433
tyrosine
1315
calcium
1099
TNF
1095
cAMP
724
glucose
679
MAP
672
serine
623
nitric oxide
535
MTT
511
threonine
488
acetate
416
Clin
406
ATP
385
MDA
357
water
338
sodium
313
more...