Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: HUMANGGP:011708 (
HER2
)
12,650
document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
HER2
12650
epidermal growth factor receptor
1626
neu
1571
EGFR
1372
estrogen receptor
1310
Mol
946
progesterone receptor
893
tyrosine kinase
801
p53
784
Sep
721
hormone receptor
626
HER3
543
erbB-2
517
AKT
441
PI3K
425
Ki-67
400
EGF receptor
358
mTOR
356
ERBB2
347
epidermal growth factor
306
more...
Disease
breast cancer
7340
cancer
5673
tumor
5218
carcinoma
1222
metastatic breast cancer
1013
metastases
977
tumor growth
534
gastric cancer
449
adenocarcinoma
438
tumorigenesis
408
MCF
382
ductal carcinoma
355
tumor progression
350
lung cancer
325
carcinogenesis
290
ovarian cancer
270
primary tumor
267
non-small cell lung cancer
245
ductal carcinoma in situ
225
Luminal
202
more...
Symptom
diarrhea
102
fatigue
62
nausea
52
pain
50
vomiting
26
headache
21
overweight
18
dyspnea
17
abdominal pain
16
anorexia
14
nipple discharge
12
nipple discharge
12
chills
11
nausea and vomiting
11
weakness
9
back pain
9
asthenia
8
erythema
7
arthralgia
7
decreased appetite
7
more...
Drug
Herceptin
1124
DM1
176
Gefitinib
78
Pertuzumab
69
lysine
57
Cetuximab
53
CSF
44
IFN-gamma
43
Bevacizumab
43
Docetaxel
39
ROS
32
Paraffin
31
Erlotinib
31
Taxol
30
MAP
29
ROC
27
IL-2
27
Fulvestrant
25
NVP
24
Everolimus
23
more...
Enzyme
ERK
11271
mitogen-activated protein kinase
468
focal adhesion kinase
193
PARP
144
MEK
143
protein kinase
131
phosphatidylinositol 3-kinase
71
topoisomerase
67
topoisomerase
66
luciferase
59
caspase-3
57
ACS
53
phosphoinositide 3-kinase
51
cdc2
46
urokinase-type plasminogen activator
44
proteasome
43
protein kinase C
30
P-glycoprotein
29
AMP-activated protein kinase
26
CD10
26
more...
Compound
DNA
903
Dec
852
Clin
819
tyrosine
609
MDA
401
methionine
222
Luminal
202
MEK
115
ATP
111
PEG
97
TNM
82
CAM
80
oxygen
76
cysteine
75
MTT
74
CAP
73
PEG
70
CAP
66
DFS
65
lysine
65
more...