Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: HUMANGGP:010955 (mda-7)
464 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The hips of 8 young volunteers were investigated with high resolution MRI. The purpose of this study was to establish an imaging protocol to visualize hyaline cartilage, synovial fluid, and subchondral bone with optimized contrast. Spin Echo (SE) and Gradient Echo (GE) sequences were compared. FISP with a flip angle of 70 degrees was superior to the other techniques. The same sequences were applied on 45 volunteers aged 65-93 years. Early signs of degenerative arthritis of the hip were demonstrated as thinning, variable signal intensities within the cartilage layer, and cartilage loss. MRI of the hip may be a useful tool for the detection of early degenerative cartilage damage which cannot be documented with conventional x-rays.
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PMID:[Early signs of arthrosis of the hip joint in MRT]. 281 56