Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: HUMANGGP:010529 (
cytochrome P450
)
25,071
document(s) hit in 31,850,051 MEDLINE articles (0.02 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
cytochrome P450
25071
P450
4873
microsomal
2735
CYP3A4
2375
CYP1A2
1771
Sep
1703
NADPH
1645
Mol
1638
CYP2D6
1462
CYP3A
1353
CYP1A1
1276
CYP2C9
1197
cytochrome
1138
CYP2E1
1108
xenobiotic
1087
CYP2C19
1027
reductase
950
CYP
859
P-glycoprotein
646
glutathione S-transferase
622
more...
Disease
cancer
1416
tumor
664
carcinogenesis
585
GSH
480
hepatocellular carcinoma
377
breast cancer
361
hypertension
351
HIV
346
diabetes
239
depression
214
lung cancer
165
tuberculosis
160
MCF
143
obesity
139
immunodeficiency
135
liver disease
133
Mycobacterium
130
NAME
124
prostate cancer
122
carcinoma
116
more...
Symptom
pain
163
seizures
121
diarrhea
84
nausea
80
headache
79
anesthesia
74
vomiting
58
dizziness
45
fatigue
41
sleepiness
39
starvation
33
hepatomegaly
30
nausea and vomiting
29
analgesia
28
insomnia
26
constipation
25
hyperoxia
24
tremor
20
weakness
20
agitation
17
more...
Drug
caffeine
244
NADH
204
Ketoconazole
113
FAD
112
ascorbate
85
vitamin E
76
Clopidogrel
75
Monit
75
Cardiovasc
74
Ethanol
73
Glutathione
71
lysine
70
EE2
70
PCB
65
ROS
63
MAP
63
Dermatol
53
ABC
50
Heme
48
Mutagen
47
more...
Enzyme
CYP3A4
2379
glutathione S-transferase
754
P-glycoprotein
648
demethylase
633
UDP-glucuronosyltransferase
428
catalase
420
superoxide dismutase
357
soluble epoxide hydrolase
290
peroxidase
258
alanine aminotransferase
247
reverse transcriptase
220
lipoxygenase
203
CPR
200
glutathione peroxidase
193
NQO1
189
protein kinase
178
luciferase
171
flavin-containing monooxygenase
164
mitogen-activated protein kinase
162
aldehyde dehydrogenase
160
more...
Compound
Dec
1860
DNA
1760
NADPH
1646
NADPH
1645
Clin
1499
oxygen
1150
water
880
iron
699
pyrene
606
GSH
534
GSH
534
hydrogen
519
sodium
505
ethanol
430
calcium
392
nitric oxide
380
glucose
318
phosphate
305
CO2
295
nitrogen
283
more...