Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: HUMANGGP:010292 (PI3K)
 23,446 document(s) hit in 31,850,051 MEDLINE articles (0.04 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
PI3K 23446
AKT 7483
mTOR 4856
MAPK 3370
ERK 2571
Mol 2363
PTEN 1738
insulin 1470
MEK 1403
Sep 1391
caspase-3 1292
ERK1 1283
p53 1170
Bcl-2 1161
p38 1154
EGFR 861
cytokine 856
JNK 834
TNF 774
protein kinase B 666
more...
Disease
cancer 7070
tumor 4968
breast cancer 1579
tumor growth 1140
tumorigenesis 1124
tumor progression 689
hepatocellular carcinoma 665
carcinoma 617
diabetes 606
prostate cancer 599
lung cancer 594
colorectal cancer 545
carcinogenesis 538
melanoma 488
leukemia 442
adenocarcinoma 430
glioma 425
ischemia 421
non-small cell lung cancer 369
obesity 368
more...
Symptom
starvation 138
pain 87
seizures 56
functional recovery 48
collapse 39
diarrhea 36
fatigue 25
exhaustion 20
respiratory distress 16
anesthesia 15
cachexia 14
splenomegaly 13
ataxia 12
nausea 11
weakness 11
memory loss 11
Scratch 10
cough 10
skin damage 8
vomiting 8
more...
Drug
ROS 465
NVP 129
MAP 114
Monit 110
IL-2 95
lysine 77
CSF 72
Dermatol 60
Herceptin 59
Sorafenib 48
Everolimus 47
IFN-gamma 46
Cardiovasc 45
GEO 40
Gefitinib 34
ICI 34
uPA 33
Cetuximab 33
Imatinib 31
Glucagon 24
more...
Enzyme
mitogen-activated protein kinase 5145
ERK 4331
MEK 1658
focal adhesion kinase 1430
protein kinase 1086
caspase-3 1002
protein kinase C 697
phosphoinositide 3-kinase 575
AMP-activated protein kinase 500
phosphatidylinositol 3-kinase 487
GSK 486
luciferase 450
PARP 421
AMPK 413
AMPK 410
superoxide dismutase 275
PDK1 256
caspase-9 212
proteasome 201
calcineurin 146
more...
Compound
Dec 1557
DNA 1477
MEK 1389
glucose 1288
oxygen 1272
tyrosine 836
TNF 774
Clin 600
MTT 584
calcium 519
MDA 424
serine 360
ATP 346
cAMP 337
Insulin 312
nitric oxide 307
threonine 287
water 273
methionine 228
phosphate 220
more...