Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: HUMANGGP:010225 (BRAF)
 9,540 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
BRAF 9540
KRAS 1860
MEK 1624
NRAS 1129
MAPK 957
ERK 911
EGFR 850
p53 802
Mol 780
RAF 661
PIK3CA 642
Sep 591
RET 445
PTEN 430
epidermal growth factor receptor 396
PI3K 372
Raf-1 368
AKT 367
KIT 332
ALK 322
more...
Disease
cancer 3895
tumor 3644
melanoma 3198
colorectal cancer 1197
metastatic melanoma 917
carcinoma 917
metastases 702
Melanoma 600
tumorigenesis 482
thyroid cancer 419
papillary thyroid cancer 414
adenocarcinoma 362
tumor growth 330
lung cancer 324
carcinogenesis 302
cutaneous melanoma 242
tumor progression 242
sarcoma 222
colon cancer 219
non-small cell lung cancer 210
more...
Symptom
fatigue 61
seizures 46
diarrhea 40
nausea 34
headache 29
arthralgia 23
splenomegaly 22
pain 22
dyspnea 14
abdominal pain 12
vomiting 10
bone pain 10
ataxia 9
hypotonia 9
anorexia 8
chills 8
cough 7
starvation 7
weakness 7
erythema 7
more...
Drug
Dermatol 308
PTC 151
MAP 67
Sorafenib 61
ROS 44
Ipilimumab 42
Cetuximab 30
lysine 22
IL-2 16
Imatinib 14
Paraffin 13
CSF 13
PDL 12
ETS 12
TAK 10
PCP 9
Nexavar 9
ABC 8
Gefitinib 8
Erlotinib 8
more...
Enzyme
ERK 2757
mitogen-activated protein kinase 1952
MEK 1876
protein kinase 436
focal adhesion kinase 193
APC 180
MAP 67
phosphatidylinositol 3-kinase 62
phosphoinositide 3-kinase 54
MEKK1 50
lactate dehydrogenase 49
proteasome 45
protein kinase C 37
PARP 37
caspase-3 33
STK11 33
AMPK 32
AMP-activated protein kinase 28
succinate dehydrogenase 26
isocitrate dehydrogenase 26
more...
Compound
MEK 1608
DNA 1274
Dec 637
Clin 569
methionine 281
tyrosine 212
ATP 117
iodine 104
serine 98
threonine 98
Thyroid 94
cAMP 78
oxygen 74
GTP 69
MAP 67
valine 61
glucose 56
calcium 50
TNM 46
MTT 41
more...