Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: HUMANGGP:010085 (PARP1)
 1,615 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
PARP1 1615
PARP 430
ADP 283
poly(ADP-ribose) polymerase 247
Mol 212
BRCA1 181
Poly 175
PAR 127
NAD 115
p53 115
caspase-3 109
PARP-2 108
Poly(ADP-ribose) polymerase 92
XRCC1 89
Sep 84
histone 74
ATM 65
DNA-dependent protein kinase 63
BRCA2 62
poly (ADP-ribose) polymerase 1 56
more...
Disease
cancer 570
tumor 271
breast cancer 178
ATM 71
ovarian cancer 55
tumor growth 46
tumorigenesis 35
hepatocellular carcinoma 35
prostate cancer 35
carcinogenesis 33
leukemia 33
carcinoma 28
lung cancer 27
tumor progression 24
Alzheimer's disease 22
ischemia 21
colorectal cancer 21
glioma 20
acute myeloid leukemia 19
Parkinson's disease 19
more...
Symptom
collapse 14
starvation 8
ataxia 5
functional recovery 4
pain 2
fatigue 2
seizures 2
consciousness disturbance 1
memory loss 1
sore throat 1
hepatomegaly 1
exhaustion 1
cerebellar ataxia 1
weakness 1
Drug
ROS 36
lysine 31
NADH 9
BLM 9
ETS 8
niacin 4
Mutagen 3
CTX 3
Dermatol 3
Monit 3
TTC 2
PBZ 2
GEO 2
caffeine 2
vitamin E 2
Cardiovasc 2
ascorbate 2
ROC 2
AraC 2
CTT 1
more...
Enzyme
PARP 467
ERK 65
caspase-3 61
mitogen-activated protein kinase 42
DNA ligase 24
DNA ligase 24
topoisomerase 23
topoisomerase 22
proteasome 20
poly(ADP-ribose) glycohydrolase 20
DNA polymerase 19
protein kinase 17
catalase 15
caspase-9 15
AMP-activated protein kinase 15
ATPase 14
endonuclease 13
superoxide dismutase 13
focal adhesion kinase 12
ACS 11
more...
Compound
DNA 970
ADP-ribose 316
ADP 300
ADP 283
ADP 283
NAD 150
PAR 127
NAD 115
Dec 102
oxygen 92
nicotinamide 60
ATP 51
MDA 40
lysine 34
hydrogen 28
Clin 25
glucose 23
MTT 20
serine 20
TNF 18
more...