Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: HUMANGGP:010082 (PARP-1)
 2,521 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
PARP-1 2521
PARP 667
poly(ADP-ribose) polymerase 649
caspase-3 415
ADP 397
Mol 292
Poly(ADP-ribose) polymerase 291
NAD 271
Poly 266
p53 243
Bcl-2 220
PAR 161
ATP 158
Sep 146
PARP-2 141
poly (ADP-ribose) polymerase 140
cytochrome c 121
apoptosis-inducing factor 98
caspase-9 97
NAD+ 94
more...
Disease
cancer 634
tumor 270
breast cancer 126
ischemia 118
diabetes 93
stroke 82
carcinogenesis 64
tumor growth 63
carcinoma 61
MCF 59
leukemia 53
ATM 51
Alzheimer's disease 49
prostate cancer 46
ovarian cancer 42
tumorigenesis 41
GSH 39
cerebral ischemia 39
hepatocellular carcinoma 39
Parkinson's disease 37
more...
Symptom
collapse 17
pain 7
hypothermia 7
seizures 6
starvation 5
respiratory distress 5
hyperoxia 5
nausea 4
exhaustion 4
ataxia 4
diarrhea 4
fatigue 3
anesthesia 3
analgesia 2
skin damage 2
asthenia 2
stomach pain 2
functional recovery 2
vomiting 2
weakness 2
more...
Drug
ROS 67
NADH 16
lysine 13
caffeine 9
vitamin E 8
Arsenic trioxide 8
niacin 7
Monit 5
Cardiovasc 5
Mutagen 5
ascorbate 5
BLM 5
Ethanol 5
IL-2 5
Dermatol 4
CSF 4
DNase I 4
TTC 4
MAP 4
ETS 3
more...
Enzyme
PARP 2521
caspase-3 344
mitogen-activated protein kinase 129
caspase-9 80
ERK 69
caspase-8 58
poly(ADP-ribose) glycohydrolase 51
superoxide dismutase 41
DNA ligase 28
DNA ligase 28
catalase 28
proteasome 25
DNA polymerase 25
lactate dehydrogenase 24
protein kinase 23
NADPH oxidase 20
AMP-activated protein kinase 20
topoisomerase 20
NADPH oxidase 20
luciferase 20
more...
Compound
DNA 1260
ADP-ribose 600
ADP 419
ADP 398
ADP 397
NAD 360
oxygen 294
NAD 271
Dec 167
PAR 161
ATP 158
nicotinamide 135
hydrogen 82
3-aminobenzamide 82
glucose 67
TNF 62
zinc 61
MTT 59
MDA 56
calcium 53
more...