Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: HUMANGGP:008694 (
EGFR
)
13,873
document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
EGFR
13873
tyrosine kinase
2251
epidermal growth factor receptor
1639
HER2
1372
Mol
1220
KRAS
1216
p53
1151
EGF
964
PI3K
861
BRAF
850
AKT
813
ERK
808
Sep
784
epidermal growth factor
724
ALK
720
MAPK
712
MET
547
PTEN
498
mTOR
491
EGF receptor
449
more...
Disease
cancer
5968
tumor
4582
lung cancer
1910
non-small cell lung cancer
1683
breast cancer
1353
adenocarcinoma
1174
colorectal cancer
822
carcinoma
718
tumor growth
664
tumorigenesis
587
glioblastoma
545
metastases
536
squamous cell carcinoma
520
lung carcinoma
437
tumor progression
428
glioma
403
carcinogenesis
384
MCF
278
hepatocellular carcinoma
219
prostate cancer
211
more...
Symptom
diarrhea
106
pain
32
fatigue
32
nausea
30
cough
24
vomiting
16
dyspnea
13
headache
13
starvation
13
anorexia
11
seizures
9
shortness of breath
9
hemoptysis
8
HSA
7
dry skin
7
exhaustion
7
abdominal pain
7
erythema
7
cachexia
6
chest pain
6
more...
Drug
Gefitinib
265
Cetuximab
186
Erlotinib
177
ROS
100
Herceptin
94
Dermatol
86
Bevacizumab
52
Tarceva
42
MAP
38
Panitumumab
35
lysine
35
GEO
30
Imatinib
24
CSF
21
Sorafenib
21
Paraffin
19
Monit
19
uPA
19
ABC
18
ICI
17
more...
Enzyme
ERK
13873
mitogen-activated protein kinase
1365
MEK
503
focal adhesion kinase
482
protein kinase
219
protein kinase C
150
PARP
124
caspase-3
105
luciferase
99
phosphatidylinositol 3-kinase
79
APC
75
proteasome
69
ACS
54
phosphoinositide 3-kinase
49
STK11
47
urokinase-type plasminogen activator
45
ATPase
41
cdc2
40
MMP
39
AMPK
39
more...
Compound
DNA
1286
tyrosine
1085
Dec
908
Clin
645
methionine
633
MEK
413
MDA
319
ATP
228
MTT
198
oxygen
188
calcium
128
TNF
117
glucose
103
serine
102
quinazoline
100
quinazoline
100
water
92
hydrogen
80
threonine
80
cysteine
78
more...