Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: HUMANGGP:007269 (
HDAC1
)
2,282
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
HDAC1
2282
histone
906
histone deacetylase
782
HDAC2
496
HDAC
298
HDAC3
277
Mol
254
histone H3
215
Histone deacetylase
189
HDAC6
187
p53
177
Sep
146
DNMT1
133
p300
131
p21
116
HDAC4
114
HDAC8
110
Sp1
77
transcriptional repressor
68
histone deacetylase 1
62
more...
Disease
cancer
627
tumor
378
breast cancer
108
tumorigenesis
77
leukemia
73
tumor growth
71
carcinogenesis
52
prostate cancer
50
carcinoma
45
tumor progression
42
MCF
41
retinoblastoma
41
colon cancer
37
hepatocellular carcinoma
37
acute myeloid leukemia
34
colorectal cancer
34
lung cancer
31
adenocarcinoma
30
lymphoma
24
HIV
23
more...
Symptom
pain
9
starvation
5
seizures
4
functional recovery
3
fatigue
3
weakness
2
splenomegaly
2
nausea
2
hyperoxia
2
acidity
1
vomiting
1
cachexia
1
HSA
1
polyuria
1
Halo
1
Neuropathic pain
1
Noise-induced hearing loss
1
Drug
lysine
180
Vorinostat
21
ROS
12
Romidepsin
8
Dermatol
7
Gel
6
IL-2
5
Imatinib
4
IFN-gamma
4
NADH
4
Asthma
3
GEO
3
Bortezomib
3
DNase I
3
ADR
3
Gleevec
3
ETS
3
Compound 9
3
Monit
2
MAP
2
more...
Enzyme
histone acetyltransferase
59
ERK
55
luciferase
54
mitogen-activated protein kinase
51
protein kinase
49
RNA polymerase
47
DNA methyltransferase
41
TSA
34
focal adhesion kinase
34
caspase-3
28
ACS
27
demethylase
26
proteasome
26
PARP
21
histone demethylase
18
glutathione S-transferase
16
cdc2
13
calcineurin
11
ATPase
10
protein kinase C
9
more...
Compound
DNA
464
Histone
226
lysine
210
Dec
123
zinc
73
sodium
51
oxygen
41
benzamide
34
MDA
33
TNF
32
glucose
31
ACS
27
ACS
27
retinoic acid
26
serine
25
Valproic acid
20
phosphate
19
ATP
18
MTT
18
Clin
18
more...