Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: HUMANGGP:007137 (
KRAS
)
6,632
document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
KRAS
6632
BRAF
1860
EGFR
1216
p53
1194
NRAS
892
PIK3CA
783
epidermal growth factor receptor
656
Mol
589
MEK
426
MAPK
408
Sep
383
PTEN
370
ERK
351
PI3K
338
AKT
328
APC
302
HRAS
297
ALK
293
RAF
259
tyrosine kinase
234
more...
Disease
cancer
3391
tumor
2893
colorectal cancer
1670
adenocarcinoma
1107
lung cancer
733
carcinoma
582
tumorigenesis
481
non-small cell lung cancer
459
pancreatic cancer
416
carcinogenesis
373
metastases
366
colon cancer
313
APC
302
tumor growth
282
tumor progression
200
adenoma
174
primary tumor
150
breast cancer
140
lung carcinoma
134
melanoma
126
more...
Symptom
diarrhea
29
fatigue
21
splenomegaly
13
abdominal pain
11
nausea
9
starvation
8
pain
8
anorexia
6
hypotonia
6
chest pain
6
cough
5
seizures
5
dyspnea
5
vomiting
4
exhaustion
4
cachexia
4
discomfort
3
hepatosplenomegaly
3
headache
3
discomfort
3
more...
Drug
Cetuximab
91
Panitumumab
41
MAP
28
Bevacizumab
23
lysine
23
ROS
20
PTC
14
NVP
12
MDS
12
Oxaliplatin
11
Dermatol
10
Gefitinib
9
ascorbate
9
CSF
9
CDX
8
Leucovorin
8
CDX
8
GEO
8
Erlotinib
7
Irinotecan
6
more...
Enzyme
ERK
2058
mitogen-activated protein kinase
686
MEK
514
APC
302
focal adhesion kinase
153
STK11
82
protein kinase
56
phosphatidylinositol 3-kinase
49
phosphoinositide 3-kinase
37
luciferase
36
PARP
30
MAP
27
IKK
25
proteasome
23
caspase-3
23
ACS
22
CD10
18
AMP-activated protein kinase
18
reverse transcriptase
16
ATPase
15
more...
Compound
DNA
1229
MEK
424
Dec
407
Clin
345
methionine
239
tyrosine
100
oxygen
77
GTP
77
glucose
50
ATP
37
glutamine
36
TNM
34
GDP
34
serine
34
5-FU
32
lysine
30
cysteine
29
MAP
27
MTT
25
phosphate
24
more...